Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8928710 | 0.87 | RECQL (0.38) | KDM4EHSD17B10SMN1; SMN2RECQLOPRK1 | |
| SCHEMBL8928561 | 0.77 | RECQL (0.38) | KDM4EHSD17B10SMN1; SMN2RECQLOPRK1 | |
| SCHEMBL8928637 | 0.76 | MEN1 (0.42) | KDM4ESMN1; SMN2RECQLOPRK1HPGD | |
| SCHEMBL8928766 | 0.76 | OPRK1 (0.42) | KDM4EHSD17B10SMN1; SMN2RECQLOPRK1 | |
| SCHEMBL8928631 | 0.73 | MEN1 (0.39) | KDM4EHSD17B10SMN1; SMN2RECQLOPRK1 | |
| SCHEMBL8928429 | 0.73 | MEN1 (0.35) | KDM4EHSD17B10SMN1; SMN2RECQLCYP1A2 | |
| SCHEMBL8928945 | 0.71 | OPRK1 (0.44) | KDM4ESMN1; SMN2RECQLOPRK1HPGD | |
| SCHEMBL8928579 | 0.71 | OPRK1 (0.43) | SMN1; SMN2RECQLOPRK1HPGDBRD4 | |
| SCHEMBL2442196 | 0.69 | GABRA1 (0.57) | OPRK1HPGDGABRA1GABRA5GABRA2 | |
| SCHEMBL8928531 | 0.68 | HPGD (0.41) | KDM4ESMN1; SMN2RECQLHPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0776892-A1 | THIENYLAZOLE COMPOUND AND THIENOTRIAZOLODIAZEPINE COMPOUND | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-06-04 | — | — | EP | disclosed |