Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CCKAR | P32238 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | PTAFR | P25105 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8928668 | 0.88 | PTAFR (0.38) | MEN1KMT2ACCKARL3MBTL1OPRK1 | |
| SCHEMBL8928732 | 0.87 | OPRK1 (0.44) | MEN1KMT2ACCKARL3MBTL1OPRK1 | |
| SCHEMBL8928869 | 0.84 | L3MBTL1 (0.36) | MEN1KMT2ACCKARL3MBTL1ALDH1A1 | |
| SCHEMBL8928667 | 0.82 | OPRK1 (0.44) | MEN1KMT2ACCKAROPRK1GABRA1 | |
| SCHEMBL8928637 | 0.82 | MEN1 (0.42) | MEN1KMT2ACCKARL3MBTL1OPRK1 | |
| SCHEMBL8928440 | 0.79 | OPRK1 (0.55) | MEN1KMT2ACCKAROPRK1PTAFR | |
| SCHEMBL8928710 | 0.75 | RECQL (0.38) | MEN1KMT2ACCKAROPRK1ALDH1A1 | |
| SCHEMBL8928940 | 0.73 | KDM4E (0.36) | OPRK1ALDH1A1CYP1A2GABRA1GABRA5 | |
| SCHEMBL8689007 | 0.73 | MEN1 (0.42) | MEN1KMT2ACCKARL3MBTL1ALDH1A1 | |
| SCHEMBL8928678 | 0.71 | MEN1 (0.39) | MEN1KMT2ACCKARL3MBTL1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0776892-A1 | THIENYLAZOLE COMPOUND AND THIENOTRIAZOLODIAZEPINE COMPOUND | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-06-04 | — | — | EP | disclosed |