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SCHEMBL8929106

SCHEMBL8929106

C1CC[SiH2]OC1.Oc1cccc(N(c2ccccc2)c2ccc(-c3ccc(N(c4ccccc4)c4cccc(O)c4)cc3)cc2)c1

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 2/20 0.35
▸ CYP3A4 P08684 2/20 0.35
▸ TSHR P16473 1/20 0.34
▸ HSD17B1 P14061 4/20 0.33
▸ HSD17B2 P37059 4/20 0.33
▸ CYP2C9 P11712 1/20 0.33
▸ ADRA2A P08913 1/20 0.32
▸ ADRA1A P35348 1/20 0.32
▸ HTR7 P34969 1/20 0.30
▸ ADAMTS4 O75173 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8928683 0.89 MMP3 (0.39) ALDH1A1CYP3A4CYP2C9
SCHEMBL223856 0.80 HSD17B1 (0.50) ALDH1A1CYP3A4TSHRHSD17B1HSD17B2
SCHEMBL913348 0.80 HSD17B1 (0.50) ALDH1A1CYP3A4TSHRHSD17B1HSD17B2
SCHEMBL504209 0.80 HSD17B1 (0.50) ALDH1A1CYP3A4TSHRHSD17B1HSD17B2
SCHEMBL2623461 0.79 HSD17B1 (0.54) ALDH1A1CYP3A4TSHRHSD17B1HSD17B2
SCHEMBL9136317 0.79 HSD17B1 (0.54) ALDH1A1CYP3A4TSHRHSD17B1HSD17B2
Water SCHEMBL913259 0.79 CYP3A4 (0.48) ALDH1A1CYP3A4TSHRHSD17B1HSD17B2
SCHEMBL13104514 0.77 HSD17B1 (0.53) ALDH1A1CYP3A4TSHRHSD17B1HSD17B2
Phenol SCHEMBL2420081 0.77 CA12 (0.44) —
Phenol SCHEMBL9243036 0.77 CA12 (0.44) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5674635-A Electroluminescent device XEROX CORPORATION (US) 1997-10-07 — — US claimed