Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 12/20 | 0.69 |
| ▸ | RXRA | P19793 | 10/20 | 0.69 |
| ▸ | RXRB | P28702 | 9/20 | 0.69 |
| ▸ | RXRG | P48443 | 6/20 | 0.69 |
| ▸ | NR4A1 | P22736 | 3/20 | 0.69 |
| ▸ | NR4A3 | Q92570 | 3/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.69 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.69 |
| ▸ | C5 | P01031 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.69 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.69 |
| ▸ | DRD2 | P14416 | 1/20 | 0.69 |
| ▸ | HPGD | P15428 | 1/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.69 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.69 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.69 |
| ▸ | HTR2A | P28223 | 1/20 | 0.69 |
| ▸ | HTR2C | P28335 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18063471 | 0.90 | NR4A2 (0.71) | NR4A2RXRARXRBRXRGNR4A1 | |
| SCHEMBL14867495 | 0.89 | NR4A2 (0.73) | NR4A2RXRARXRBRXRGNR4A1 | |
| SCHEMBL8929931 | 0.86 | NR4A2 (0.68) | NR4A2RXRARXRBRXRGNR4A1 | |
| SCHEMBL8550570 | 0.85 | NR4A2 (0.57) | NR4A2RXRARXRBRXRGNR4A1 | |
| SCHEMBL9024857 | 0.85 | PTGS2 (0.64) | NR4A2RXRARXRBRXRGNR4A1 | |
| SCHEMBL8547030 | 0.85 | NR4A2 (0.57) | NR4A2RXRARXRBRXRGNR4A1 | |
| SCHEMBL11719710 | 0.83 | NR4A2 (0.65) | NR4A2RXRARXRBRXRGNR4A1 | |
| SCHEMBL7492453 | 0.83 | NR4A2 (0.66) | NR4A2RXRARXRBRXRGNR4A1 | |
| SCHEMBL13653143 | 0.83 | NR4A2 (0.65) | NR4A2RXRARXRBRXRGNR4A1 | |
| Oxaprozin SCHEMBL3286 | 0.82 | RXRA (1.00) | NR4A2RXRARXRBRXRGNR4A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090247488-A1 | ANTI-INFLAMMATORY PHOSPHONATE COMPOUNDS | CANNIZZARO CARINA | 2009-10-01 | — | — | US | disclosed |
| US-20090247488-A1 | ANTI-INFLAMMATORY PHOSPHONATE COMPOUNDS | CANNIZZARO CARINA | 2009-10-01 | — | — | US | disclosed |
| US-7432261-B2 | Anti-inflammatory phosphonate compounds | GILEAD SCIENCES, INC. (US) | 2008-10-07 | — | — | US | disclosed |
| US-7432261-B2 | Anti-inflammatory phosphonate compounds | GILEAD SCIENCES, INC. (US) | 2008-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090247488-A1 | ANTI-INFLAMMATORY PHOSPHONATE COMPOUNDS | PHOSPHO1, TNF, PTGES | NR4A2 1050/4885RXRA 1906/4885RXRB 2036/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.