Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.53 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CLK2 | P49760 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8388932 | 0.89 | KCNH2 (0.52) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| Trifluoroacetic Acid SCHEMBL8929952 | 0.88 | ALDH1A1 (0.62) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL8925207 | 0.84 | ALDH1A1 (0.49) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL8740993 | 0.80 | ALDH1A1 (0.56) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL8385056 | 0.79 | KCNH2 (0.51) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL8385634 | 0.78 | KCNH2 (0.56) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| Trifluoroacetic Acid SCHEMBL8388928 | 0.78 | KCNH2 (0.61) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL7511355 | 0.78 | KCNH2 (0.65) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL7506628 | 0.77 | ALDH1A1 (0.53) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL7518993 | 0.75 | KCNH2 (0.51) | ALDH1A1POLBOPRM1CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0812838-A1 | PYRIDONECARBOXYLIC ACID DERIVATIVE SUBSTITUTED BY BICYCLIC AMINO GROUP, ESTER THEREOF, SALT THEREOF, AND BICYCLIC AMINE AS INTERMEDIATE THEREFOR | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1997-12-17 | — | — | EP | disclosed |