Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 12/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | FFAR2 | O15552 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8930605 | 0.88 | CYP11B2 (0.36) | CYP19A1CYP3A4 | |
| SCHEMBL8581331 | 0.84 | CYP19A1 (0.39) | CYP19A1TSHRMAPK1HIF1ATDP1 | |
| SCHEMBL8930574 | 0.81 | CYP19A1 (0.36) | CYP19A1TSHRMAPK1HIF1ATDP1 | |
| SCHEMBL8930562 | 0.79 | CYP19A1 (0.36) | CYP19A1CYP3A4 | |
| SCHEMBL8930577 | 0.75 | L3MBTL1 (0.33) | CYP19A1L3MBTL1 | |
| SCHEMBL27464965 | 0.73 | TSHR (0.38) | TSHRCYP3A4L3MBTL1FFAR2 | |
| SCHEMBL8558949 | 0.73 | — | — | |
| SCHEMBL8566396 | 0.70 | PDE2A (0.33) | — | |
| SCHEMBL8930614 | 0.68 | IDO1 (0.34) | CYP19A1 | |
| SCHEMBL8561977 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0764641-A1 | NOVEL 4,5-DISUBSTITUTED PYRIMIDINE DERIVATIVE AND HERBICIDE | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1997-03-26 | — | — | EP | disclosed |
| CN-1133589-A | Novel pyrimidine derivative, herbicide and plant growth regulator | NISSAN CHEMICAL IND LTD (JP) | 1996-10-16 | — | — | CN | disclosed |