Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | FFAR2 | O15552 | 9/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8930604 | 0.82 | FFAR2 (0.33) | TSHRFFAR2CNR2L3MBTL1 | |
| SCHEMBL8581331 | 0.75 | CYP19A1 (0.39) | TSHRCYP3A4 | |
| SCHEMBL8930547 | 0.73 | CYP19A1 (0.40) | TSHRFFAR2CYP3A4L3MBTL1 | |
| SCHEMBL8930574 | 0.72 | CYP19A1 (0.36) | TSHR | |
| SCHEMBL8930562 | 0.70 | CYP19A1 (0.36) | CYP3A4 | |
| SCHEMBL8930577 | 0.67 | L3MBTL1 (0.33) | L3MBTL1 | |
| SCHEMBL8565951 | 0.66 | ADORA1 (0.44) | — | |
| SCHEMBL8566396 | 0.66 | PDE2A (0.33) | — | |
| SCHEMBL6195873 | 0.64 | TSHR (0.59) | TSHRFFAR2HDAC4HDAC7HDAC5 | |
| SCHEMBL8561977 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1133589-A | Novel pyrimidine derivative, herbicide and plant growth regulator | NISSAN CHEMICAL IND LTD (JP) | 1996-10-16 | — | — | CN | disclosed |