Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MME | P08473 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.36 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CPA1 | P15085 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9268407 | 0.82 | EGFR (0.44) | GSRALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL513919 | 0.79 | GSR (0.44) | GSRALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL2029476 | 0.77 | MAPT (0.41) | GSRALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL1306532 | 0.76 | SIGMAR1 (0.42) | GSRALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL6129084 | 0.76 | GSR (0.42) | GSRALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL27790191 | 0.75 | CYP3A4 (0.44) | GSRALDH1A1LMNAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL21219507 | 0.74 | GSR (0.41) | GSRALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL27524142 | 0.74 | ALDH1A1 (0.50) | GSRALDH1A1LMNAL3MBTL1HTT | |
| SCHEMBL2793715 | 0.74 | GRM7 (0.58) | ALDH1A1LMNAMMEMEN1KMT2A | |
| SCHEMBL594168 | 0.72 | GSR (0.44) | GSRALDH1A1MMEMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0756496-A1 | DENDRIMERIC COMPOUNDS | NYCOMED SALUTAR, INC. (US) | 1997-02-05 | — | — | EP | disclosed |
| WO-1995028966-A1 | DENDRIMERIC COMPOUNDS | NYCOMED SALUTAR INC (US) | 1995-11-02 | — | — | WO | disclosed |