SCHEMBL594168

SCHEMBL594168

O=C(O)C(CO)NC(c1ccccc1)[N+](=O)[O-]

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GSR P00390 1/20 0.44
MME P08473 1/20 0.38
KDM4E B2RXH2 1/20 0.36
ALDH1A1 P00352 1/20 0.36
MAPT P10636 1/20 0.36
CPA1 P15085 3/20 0.36
CA2 P00918 2/20 0.36
CA1 P00915 1/20 0.36
CYP2D6 P10635 1/20 0.36
SRC P12931 1/20 0.36
NAALAD2 Q9Y3Q0 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
CNR1 P21554 1/20 0.35
CNR2 P34972 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4088190 0.86 MME (0.41) MMECA2CA1MEN1KMT2A
SCHEMBL27856850 0.86 MME (0.41) MMECA2CA1MEN1KMT2A
SCHEMBL27856845 0.86 MME (0.41) MMECA2CA1MEN1KMT2A
SCHEMBL20856986 0.80 MME (0.48) MMECA2CA1NAALAD2MEN1
SCHEMBL16599215 0.80 MMP2 (0.50) CA2CA1
SCHEMBL20522203 0.77 CA1 (0.46) MMEKDM4ECA2CA1
SCHEMBL29001941 0.76 ALDH1A1 (0.44) MMEALDH1A1CYP2D6SRCNAALAD2
SCHEMBL8621292 0.76 ALDH1A1 (0.44) MMEALDH1A1CYP2D6SRCNAALAD2
SCHEMBL8621288 0.76 ALDH1A1 (0.44) MMEALDH1A1CYP2D6SRCNAALAD2
SCHEMBL28700643 0.75 LMNA (0.45) MMECYP2D6SRCNAALAD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1807515-A4 ORTHOGONAL TRANSLATION COMPONENTS FOR THE IN VIVO INCORPORATION OF UNNATURAL AMINO ACIDS SCRIPPS RESEARCH INST (US) 2008-06-18 EP claimed
EP-1807515-A2 ORTHOGONAL TRANSLATION COMPONENTS FOR THE IN VIVO INCORPORATION OF UNNATURAL AMINO ACIDS The Scripps Research Institute (US) 2007-07-18 EP claimed
WO-2006110182-A2 ORTHOGONAL TRANSLATION COMPONENTS FOR THE IN VIVO INCORPORATION OF UNNATURAL AMINO ACIDS THE SCRIPPS RESEARCH INSTITUTE (US) 2006-10-19 WO claimed
CN-1095069-A Novel process for the preparation and/or purification of clavulanic acid or pharmaceutically acceptable salts or esters thereof SMITHKLINE BEECHAM PLC (GB) 1994-11-16 CN claimed
US-20250376709-A1 PAPB AS A BIMOIETY-DEPENDENT THIOETHER INSTALLATION TOOL UNIV UTAH RES FOUND (US) 2025-12-11 US disclosed
US-12404512-B2 Method for optimizing antibody expression AMBRX, INC. (US) 2025-09-02 US disclosed
EP-3788149-B1 A METHOD FOR OPTIMIZING ANTIBODY EXPRESSION AMBRX INC (US) 2025-08-27 EP disclosed
WO-2025085723-A1 THIOETHER CROSSLINKS IN C-TERMINAL AND N-TERMINAL MODIFIED PEPTIDES UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2025-04-24 WO disclosed
WO-2025085727-A1 PAPB AS A BIMOIETY-DEPENDENT THIOETHER INSTALLATION TOOL BANDARIAN VAHE (US) 2025-04-24 WO disclosed
EP-4508235-A2 PAPB AS A BIMOIETY-DEPENDENT THIOETHER INSTALLATION TOOL University of Utah Research Foundation (US) 2025-02-19 EP disclosed
CN-119410679-A Method for optimizing antibody expression AMBRX公司 2025-02-11 CN disclosed
CN-119410678-A Method for optimizing antibody expression AMBRX公司 2025-02-11 CN disclosed
CN-1258298-A Process for preparation of metal salt of clavulanic acid SMITHKLINE BEECHAM PLC (GB) 2000-06-28 CN disclosed
CN-1041934-C Novel process SMITHKLINE BEECHAM PLC (GB) 1999-02-03 CN disclosed
CN-1179161-A Clavulanic acid extractim process SMITHKLINE BEECHAM PLC (GB) 1998-04-15 CN disclosed
CN-1037967-C novel intermediates and their use for the preparation of clavulanic acid SMITHKLINE BEECHAM PLC (GB) 1998-04-08 CN disclosed
CN-1036592-C Novel method for preparation and/or purification of clavulanic acid or pharmaceutical salt or ester of same SMITHKLINE BEECHAM PLC (GB) 1997-12-03 CN disclosed
CN-1113244-A Novel process SMITHKLINE BEECHAM PLC (GB) 1995-12-13 CN disclosed
CN-1112928-A Novel method for preparation and/or purification of clavulanic acid or pharmaceutical salt or ester of same SMITHKLINE BEECHAM PLC (GB) 1995-12-06 CN disclosed
CN-1095069-A Novel process for the preparation and/or purification of clavulanic acid or pharmaceutically acceptable salts or esters thereof SMITHKLINE BEECHAM PLC (GB) 1994-11-16 CN disclosed