SCHEMBL8930564

SCHEMBL8930564

CC(C)(C)OC(c1ccc(Cl)cc1)c1cnc(C(F)F)nc1Cl

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.32
TDO2 P48775 1/20 0.32
LMNA P02545 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
DRD3 P35462 1/20 0.30
SLC6A3 Q01959 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8930578 0.76 ALDH1A1 (0.32) LMNASMN1; SMN2
SCHEMBL8930549 0.76 TSHR (0.33) LMNASLC6A3
SCHEMBL8930606 0.75 TSHR (0.36) SMN1; SMN2
SCHEMBL8930608 0.75 HPGD (0.35) IDO1TDO2
SCHEMBL8930575 0.74 CYP19A1 (0.33) LMNASMN1; SMN2
SCHEMBL8930616 0.74 IDO1 (0.33) IDO1TDO2DRD3SLC6A3
SCHEMBL8930562 0.69 CYP19A1 (0.36) IDO1TDO2
SCHEMBL8561982 0.68
SCHEMBL8566402 0.66 APLNR (0.33)
SCHEMBL26598773 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0764641-A1 NOVEL 4,5-DISUBSTITUTED PYRIMIDINE DERIVATIVE AND HERBICIDE NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) 1997-03-26 EP disclosed