Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | TDO2 | P48775 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8930607 | 0.77 | FFAR2 (0.32) | HDAC6FFAR2 | |
| SCHEMBL8930564 | 0.74 | IDO1 (0.32) | IDO1TDO2SLC6A3DRD3 | |
| SCHEMBL8566402 | 0.69 | APLNR (0.33) | — | |
| SCHEMBL8930575 | 0.69 | CYP19A1 (0.33) | CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8930578 | 0.68 | ALDH1A1 (0.32) | — | |
| SCHEMBL8930606 | 0.68 | TSHR (0.36) | FFAR2TSHR | |
| SCHEMBL8930549 | 0.67 | TSHR (0.33) | FFAR2SLC6A3CYP2C9TSHRCYP2C19 | |
| SCHEMBL8930614 | 0.67 | IDO1 (0.34) | IDO1TDO2 | |
| SCHEMBL8930608 | 0.66 | HPGD (0.35) | IDO1TDO2HDAC6FFAR2 | |
| SCHEMBL6644684 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0764641-A1 | NOVEL 4,5-DISUBSTITUTED PYRIMIDINE DERIVATIVE AND HERBICIDE | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1997-03-26 | — | — | EP | disclosed |
| CN-1133589-A | Novel pyrimidine derivative, herbicide and plant growth regulator | NISSAN CHEMICAL IND LTD (JP) | 1996-10-16 | — | — | CN | disclosed |