SCHEMBL893078

SCHEMBL893078

CCCON1C(C)(C)CC(=O)CC1(C)C

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.38
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
HTT P42858 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4446863 1.00 GAA (0.38) GAAMEN1KMT2AHTTSMN1; SMN2
SCHEMBL6725355 0.91 GAA (0.34) GAAMEN1KMT2A
SCHEMBL2814073 0.89 GAA (0.36) GAAMEN1KMT2AHTTSMN1; SMN2
SCHEMBL2810597 0.87 GAA (0.36) GAAMEN1KMT2AHTTSMN1; SMN2
SCHEMBL13009446 0.86 GAA (0.39) GAAMEN1KMT2A
SCHEMBL2814613 0.85 MAPT (0.36) GAAMEN1KMT2AHTTSMN1; SMN2
SCHEMBL1001848 0.85 MAPT (0.36) GAAMEN1KMT2AHTTSMN1; SMN2
SCHEMBL1828803 0.85 MAPT (0.36) GAAMEN1KMT2AHTTSMN1; SMN2
SCHEMBL647676 0.85 MAPT (0.36) GAAMEN1KMT2AHTTSMN1; SMN2
SCHEMBL1703755 0.83 GAA (0.40) GAAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11161813-B2 Sterically hindered amines BASF SE (DE) 2021-11-02 US disclosed
US-20200123107-A1 STERICALLY HINDERED AMINES BASF SE (DE) 2020-04-23 US disclosed
US-20180319746-A1 STERICALLY HINDERED AMINES BASF SE (DE) 2018-11-08 US disclosed
US-10040762-B2 Sterically hindered amines BASF SE (DE) 2018-08-07 US disclosed
US-9963575-B2 Sterically hindered amine light stabilizers with a mixed functionalization BASF SE (DE) 2018-05-08 US disclosed
EP-2475655-B1 STERICALLY HINDERED AMINE STABILIZER BASF SE (DE) 2017-10-11 EP disclosed
EP-2545035-B1 STERICALLY HINDERED AMINES BASF SE (DE) 2017-08-09 EP disclosed
US-20170107352-A1 STERICALLY HINDERED AMINE LIGHT STABILIZERS WITH A MIXED FUNCTIONALIZATION BASF SE (DE) 2017-04-20 US disclosed
US-9550941-B2 Sterically hindered amine light stabilizers with a mixed functionalization BASF SE (DE) 2017-01-24 US disclosed
US-9464070-B2 Sterically hindered amine stabilizer BASF SE (DE) 2016-10-11 US disclosed
CN-100384826-C Preparation of sterically hindered amine ethers CIBA SC HOLDING AG (CH) 2008-04-30 CN disclosed
WO-2008003602-A1 PROCESS FOR THE PREPARATION OF STERICALLY HINDERED NITROXYL ETHERS CIBA HOLDING INC. (CH) 2008-01-10 WO disclosed
WO-2008003605-A1 PROCESS FOR THE PREPARATION OF STERICALLY HINDERED NITROXYL ETHERS CIBA HOLDING INC. (CH) 2008-01-10 WO disclosed
WO-2008003605-A1 PROCESS FOR THE PREPARATION OF STERICALLY HINDERED NITROXYL ETHERS CIBA HOLDING INC. (CH) 2008-01-10 WO disclosed
CN-1202085-C Preparation of sterically hindered amine ethers CIBA SC HOLDING AG (CH) 2005-05-18 CN disclosed
CN-1552758-A Preparation of sterically hindered amine ethers 西巴特殊化学品控股有限公司 2004-12-08 CN disclosed
US-6677451-B2 POLYMER STABILIZERS; OXYGEN, HEAT, RADIATION RESISTANCES; DISCOLORATION INHIBITION; COATINGS; FIBERS; TAPES; FILMS; PAPERMAKING; HALS; FIREPROOFING; OXIDATION OF A 1-ALLYL-SUBSTITUTED STERICALLY HINDERED AMINE CIBA SPECIALTY CHEMICALS CORPORATION 2004-01-13 US disclosed
US-20020094976-A1 Preparation of sterically hindered amine ethers ZEDDA ALESSANDRO (IT) 2002-07-18 US disclosed
US-6420462-B1 OXIDATION RESISTANCE, HEAT RESISTANT AND ACTINIC DEGRADATIONHETEROCYCLIC AMINE OXIDES CIBA SPECIALTY CHEMICALS CORPORATION 2002-07-16 US disclosed
US-6117995-A OXIDATION OF THE CORRESPONDING HETEROCYCLIC AMINE COMPOUND CIBA SPECIALTY CHEMICALS CORPORATION (US) 2000-09-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020094976-A1 Preparation of sterically hindered amine ethers CBR1, CBR3, RER1 GAA 4160/4885MEN1 3712/4885KMT2A 1774/4885
US-11161813-B2 Sterically hindered amines H1-0, F12, H1-2 GAA 3191/4885MEN1 586/4885KMT2A 273/4885
US-20180319746-A1 STERICALLY HINDERED AMINES H1-0, F12, H1-2 GAA 3191/4885MEN1 586/4885KMT2A 273/4885
US-20170107352-A1 STERICALLY HINDERED AMINE LIGHT STABILIZERS WITH A MIXED FUNCTIONALIZATION C1S, H1-0, H1-2 GAA 4426/4885MEN1 604/4885KMT2A 1160/4885
US-20200123107-A1 STERICALLY HINDERED AMINES H1-0, F12, H1-2 GAA 3191/4885MEN1 586/4885KMT2A 273/4885
US-10040762-B2 Sterically hindered amines H1-0, F12, H1-2 GAA 3191/4885MEN1 586/4885KMT2A 273/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.