SCHEMBL1703755

SCHEMBL1703755

CCON1C(C)(C)CC(=O)CC1(C)C

nearest known ligand 0.40

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.40
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
KDM4E B2RXH2 1/20 0.31
LMNA P02545 1/20 0.31
CYP2C19 P33261 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4446863 0.83 GAA (0.38) GAAMEN1KMT2A
SCHEMBL893078 0.83 GAA (0.38) GAAMEN1KMT2A
SCHEMBL13009446 0.81 GAA (0.39) GAAMEN1KMT2A
SCHEMBL2814073 0.80 GAA (0.36) GAAMEN1KMT2A
SCHEMBL2810597 0.79 GAA (0.36) GAAMEN1KMT2ALMNA
SCHEMBL13009238 0.78 GAA (0.37) GAAMEN1KMT2A
SCHEMBL12910935 0.78 GAA (0.37) GAAMEN1KMT2AKDM4E
SCHEMBL1001848 0.77 MAPT (0.36) GAAMEN1KMT2A
SCHEMBL2814613 0.77 MAPT (0.36) GAAMEN1KMT2A
SCHEMBL1828803 0.77 MAPT (0.36) GAAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11161813-B2 Sterically hindered amines BASF SE (DE) 2021-11-02 US disclosed
US-20200123107-A1 STERICALLY HINDERED AMINES BASF SE (DE) 2020-04-23 US disclosed
US-20180319746-A1 STERICALLY HINDERED AMINES BASF SE (DE) 2018-11-08 US disclosed
US-10040762-B2 Sterically hindered amines BASF SE (DE) 2018-08-07 US disclosed
EP-2545035-B1 STERICALLY HINDERED AMINES BASF SE (DE) 2017-08-09 EP disclosed
EP-2440557-B1 NOVEL STERICALLY HINDERED AMINE LIGHT STABILIZERS BASF SE (DE) 2017-04-05 EP disclosed
US-9045480-B2 Sterically hindered amine light stabilizers BASF SE (DE) 2015-06-02 US disclosed
US-8471031-B2 Process for the preparation of sterically hindered nitroxyl ethers BASF SE (DE) 2013-06-25 US disclosed
US-8471031-B2 Process for the preparation of sterically hindered nitroxyl ethers BASF SE (DE) 2013-06-25 US disclosed
US-8471031-B2 Process for the preparation of sterically hindered nitroxyl ethers BASF SE (DE) 2013-06-25 US disclosed
US-20100249401-A1 Process for the preparation of sterically hindered nitroxyl ethers BASF SE (DE) 2010-09-30 US disclosed
EP-2035381-A1 PROCESS FOR THE PREPARATION OF STERICALLY HINDERED NITROXYL ETHERS Ciba Holding Inc. (CH) 2009-03-18 EP disclosed
US-7361755-B2 Transition-metal-catalyzed process for the conversion of alkenes to sterically hindered substituted n-alkoxyamines CIBA SPECIALTY CHEMICALS CORPORATION (US) 2008-04-22 US disclosed
US-7361755-B2 Transition-metal-catalyzed process for the conversion of alkenes to sterically hindered substituted n-alkoxyamines CIBA SPECIALTY CHEMICALS CORPORATION (US) 2008-04-22 US disclosed
US-7361755-B2 Transition-metal-catalyzed process for the conversion of alkenes to sterically hindered substituted n-alkoxyamines CIBA SPECIALTY CHEMICALS CORPORATION (US) 2008-04-22 US disclosed
WO-2008003602-A1 PROCESS FOR THE PREPARATION OF STERICALLY HINDERED NITROXYL ETHERS CIBA HOLDING INC. (CH) 2008-01-10 WO disclosed
WO-2008003602-A1 PROCESS FOR THE PREPARATION OF STERICALLY HINDERED NITROXYL ETHERS CIBA HOLDING INC. (CH) 2008-01-10 WO disclosed
US-20050085636-A1 Transition-metal-catalyzed process for the conversion of alkenes to sterically hindered substituted n-alkoxyamines CIBA SPECIALTY CHEMICALS CORP. 2005-04-21 US disclosed
EP-1456173-A1 TRANSITION-METAL-CATALYZED PROCESS FOR THE CONVERSION OF ALKENES TO STERICALLY HINDERED SUBSTITUTED N-ALKOXYAMINES Ciba SC Holding AG (CH) 2004-09-15 EP disclosed
WO-2003053931-A1 TRANSITION-METAL-CATALYZED PROCESS FOR THE CONVERSION OF ALKENES TO STERICALLY HINDERED SUBSTITUTED N-ALKOXYAMINES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-07-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050085636-A1 Transition-metal-catalyzed process for the conversion of alkenes to sterically hindered substituted n-alkoxyamines PNMT, NNMT, TET2 GAA 3146/4885MEN1 607/4885KMT2A 167/4885
US-11161813-B2 Sterically hindered amines H1-0, F12, H1-2 GAA 3191/4885MEN1 586/4885KMT2A 273/4885
US-20180319746-A1 STERICALLY HINDERED AMINES H1-0, F12, H1-2 GAA 3191/4885MEN1 586/4885KMT2A 273/4885
US-20100249401-A1 Process for the preparation of sterically hindered nitroxyl ethers PPOX, CBR1, CBR3 GAA 1862/4885MEN1 4841/4885KMT2A 2110/4885
US-20200123107-A1 STERICALLY HINDERED AMINES H1-0, F12, H1-2 GAA 3191/4885MEN1 586/4885KMT2A 273/4885
US-10040762-B2 Sterically hindered amines H1-0, F12, H1-2 GAA 3191/4885MEN1 586/4885KMT2A 273/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.