Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 3/20 | 0.40 |
| ▸ | MC4R | P32245 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8532916 | 0.82 | CYP3A4 (0.31) | LMNAMC4RHRH1 | |
| SCHEMBL8867454 | 0.82 | CYP3A4 (0.31) | LMNAMC4RHRH1 | |
| Carbromal SCHEMBL8931182 | 0.82 | SIGMAR1 (0.35) | SIGMAR1TMEM97LMNAACHE | |
| Water SCHEMBL8931171 | 0.81 | USP2 (0.30) | LMNAMC4RHRH1 | |
| SCHEMBL8534783 | 0.80 | ALDH1A1 (0.32) | LMNAPOLBMC4RHRH1 | |
| Hydrochloric Acid SCHEMBL8867577 | 0.80 | GMNN (0.31) | LMNAMC4RHRH1 | |
| SCHEMBL8535345 | 0.79 | DRD2 (0.39) | LMNAHTR1AMC4RHRH1 | |
| SCHEMBL2475235 | 0.74 | ABCB1 (0.42) | SIGMAR1TMEM97LMNAPOLBABCB1 | |
| Acetic Acid SCHEMBL8537257 | 0.72 | MEN1 (0.38) | LMNAACHE | |
| SCHEMBL10365792 | 0.71 | CYP3A4 (0.58) | LMNAMC4RACHEHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0635009-B1 | NOVEL DERIVATIVES OF 2,3-DIHYDRO-2,2,4,6,7-PENTAALKYL-5-BENZOFURANOLS | MERRELL PHARMA INC (US) | 1997-09-17 | — | — | EP | claimed |