Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Pyrophosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrophosphoric Acid SCHEMBL8931252 | 0.85 | FDPS (0.62) | FDPSBLMTDP1CA5ACA5B | |
| Pyrophosphoric Acid SCHEMBL396637 | 0.80 | FDPS (0.91) | FDPSBLMTDP1CA2SLC34A1 | |
| Pyrophosphoric Acid SCHEMBL134995 | 0.80 | FDPS (0.91) | FDPSBLMTDP1CA2SLC34A1 | |
| Pyrophosphoric Acid SCHEMBL1859412 | 0.80 | FDPS (0.91) | FDPSBLMTDP1CA2SLC34A1 | |
| Pyrophosphoric Acid SCHEMBL14956573 | 0.80 | FDPS (0.91) | FDPSBLMTDP1CA2SLC34A1 | |
| Pyrophosphoric Acid SCHEMBL9491121 | 0.80 | FDPS (0.91) | FDPSBLMTDP1CA2SLC34A1 | |
| Pyrophosphoric Acid SCHEMBL8817259 | 0.80 | FDPS (0.91) | FDPSBLMTDP1CA2SLC34A1 | |
| Pyrophosphoric Acid SCHEMBL565350 | 0.80 | FDPS (0.91) | FDPSBLMTDP1CA2SLC34A1 | |
| Pyrophosphoric Acid SCHEMBL57948 | 0.80 | FDPS (0.91) | FDPSBLMTDP1CA2SLC34A1 | |
| Phosphoric Acid SCHEMBL569853 | 0.78 | CA5A (0.57) | CA5ACA5BCA1CA2CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0782438-A1 | ORAL COMPOSITIONS | UNILEVER N.V. (NL) | 1997-07-09 | — | — | EP | disclosed |
| WO-1996009034-A1 | ORAL COMPOSITIONS | UNILEVER N.V. (NL) | 1996-03-28 | — | — | WO | disclosed |