Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8931349 | 0.81 | ALDH1A1 (0.55) | ALDH1A1KDM4EMEN1LMNACYP1A2 | |
| SCHEMBL8712755 | 0.79 | ALDH1A1 (0.53) | ALDH1A1KDM4EMEN1LMNACYP1A2 | |
| Hydrochloric Acid SCHEMBL9359007 | 0.78 | ALDH1A1 (0.52) | ALDH1A1KDM4EMEN1LMNACYP1A2 | |
| SCHEMBL12919878 | 0.76 | ALDH1A1 (0.53) | ALDH1A1KDM4EMEN1LMNACYP1A2 | |
| SCHEMBL290725 | 0.73 | — | — | |
| SCHEMBL10667247 | 0.73 | ALDH1A1 (0.50) | ALDH1A1KDM4EMEN1LMNACYP1A2 | |
| SCHEMBL28244029 | 0.73 | ALDH1A1 (0.50) | ALDH1A1KDM4EMEN1LMNACYP1A2 | |
| SCHEMBL859923 | 0.71 | — | — | |
| SCHEMBL680649 | 0.70 | — | — | |
| SCHEMBL9355448 | 0.69 | ALDH1A1 (0.42) | ALDH1A1KDM4EMEN1LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5648498-A | Process for the preparation of 4-methyl-5-(2-chloroethyl)-thiazole and analogues thereof | ASTRA AKTIEBOLAG (SE) | 1997-07-15 | — | — | US | disclosed |
| EP-0546306-B1 | 5-(2-Chloroalkyl)-4-methylthiazoles, their preparation and their use, and intermediates for their preparation | ASTRA AB (SE) | 1997-04-16 | — | — | EP | disclosed |
| EP-0619815-B1 | PROCESS FOR THE PREPARATION OF 4-METHYL-5-(2-CHLOROETHYL)-THIAZOLE AND ANALOGUES THEREOF | ASTRA AB (SE) | 1997-04-16 | — | — | EP | disclosed |
| US-5534644-A | Process for the preparation of 4-methyl-5-(2-chloroethyl)-thiazole and analogues thereof | AKTIEBOLAGET ASTRA (SE) | 1996-07-09 | — | — | US | disclosed |