Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1F | P30939 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 10/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.37 |
| ▸ | TERT | O14746 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8181328 | 0.86 | HTR1F (0.47) | HTR1FALDH1A1HPGDMAPTNPSR1 | |
| SCHEMBL8931383 | 0.85 | ALDH1A1 (0.41) | HTR1FALDH1A1HPGDMAPTKMT2A | |
| SCHEMBL7139743 | 0.77 | HTR1F (0.68) | HTR1FALDH1A1HPGDMAPTNPSR1 | |
| SCHEMBL8181303 | 0.71 | ALDH1A1 (0.43) | HTR1FALDH1A1HPGDMAPTKMT2A | |
| SCHEMBL8181951 | 0.70 | CNR1 (0.49) | HTR1FALDH1A1HPGDKMT2AKDM4E | |
| SCHEMBL7141203 | 0.69 | HTR1F (0.73) | HTR1FALDH1A1MAPTNPSR1LMNA | |
| Benzoic Acid SCHEMBL8191205 | 0.69 | HTR1F (0.45) | HTR1FALDH1A1HPGDMAPTNPSR1 | |
| SCHEMBL7144771 | 0.69 | HTR1F (0.83) | HTR1FALDH1A1HPGDMAPTNPSR1 | |
| SCHEMBL8598857 | 0.68 | HTR1F (0.81) | HTR1FALDH1A1HPGDMAPTNPSR1 | |
| SCHEMBL7140886 | 0.68 | HTR1F (0.60) | HTR1FALDH1A1MAPTKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997013512-A1 | N-[2-SUBSTITUTED-3-(2-AMINOETHYL)-1H-INDOL-5-YL]-AMIDES: NEW 5-HT1F AGONISTS | ELI LILLY AND COMPANY (US) | 1997-04-17 | — | — | WO | disclosed |