Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HTR1F | P30939 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.37 |
| ▸ | TET3 | O43151 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | FOXO1 | Q12778 | 1/20 | 0.37 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.37 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.37 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8181303 | 0.86 | ALDH1A1 (0.43) | ALDH1A1HPGDHTR1FKDM4EALOX15 | |
| SCHEMBL8931355 | 0.85 | HTR1F (0.48) | ALDH1A1HPGDHTR1FKDM4EALOX15 | |
| SCHEMBL8181328 | 0.72 | HTR1F (0.47) | ALDH1A1HPGDHTR1FKDM4EALOX15 | |
| SCHEMBL7139743 | 0.70 | HTR1F (0.68) | ALDH1A1HPGDHTR1FKDM4EALOX15 | |
| SCHEMBL7141151 | 0.70 | L3MBTL1 (0.38) | ALDH1A1HTR1FKDM4EHDAC1HDAC2 | |
| SCHEMBL8548366 | 0.69 | KDM4E (0.38) | ALDH1A1HPGDKDM4EHSD17B10MTNR1A | |
| SCHEMBL8546818 | 0.69 | DYRK1A (0.36) | ALDH1A1HPGDKDM4EHSD17B10MTNR1A | |
| SCHEMBL8931360 | 0.67 | MLLT1 (0.42) | ALDH1A1HPGDKDM4EALOX15HSD17B10 | |
| SCHEMBL7139432 | 0.67 | HTR1F (0.61) | HTR1FHDAC1HDAC2HDAC3NCOR2 | |
| SCHEMBL7142320 | 0.64 | HTR1F (0.62) | ALDH1A1HPGDHTR1FKDM4EALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997013512-A1 | N-[2-SUBSTITUTED-3-(2-AMINOETHYL)-1H-INDOL-5-YL]-AMIDES: NEW 5-HT1F AGONISTS | ELI LILLY AND COMPANY (US) | 1997-04-17 | — | — | WO | disclosed |