Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 18/20 | 0.66 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.63 |
| ▸ | MMP2 | P08253 | 7/20 | 0.59 |
| ▸ | MMP12 | P39900 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8772607 | 0.87 | MMP13 (0.64) | MMP13FDFT1MMP2MMP12 | |
| Hydrochloric Acid SCHEMBL8772652 | 0.86 | MMP13 (0.62) | MMP13FDFT1MMP2MMP12 | |
| SCHEMBL8772564 | 0.85 | MMP13 (0.61) | MMP13FDFT1MMP2MMP12 | |
| SCHEMBL8969313 | 0.83 | MMP13 (0.62) | MMP13FDFT1MMP2MMP12 | |
| SCHEMBL9432198 | 0.83 | FDFT1 (0.76) | MMP13FDFT1MMP2MMP12 | |
| SCHEMBL8931446 | 0.82 | MMP13 (0.61) | MMP13FDFT1MMP2 | |
| SCHEMBL8709394 | 0.82 | MMP13 (0.58) | MMP13FDFT1MMP2MMP12 | |
| SCHEMBL8969946 | 0.82 | FDFT1 (0.73) | MMP13FDFT1MMP2MMP12 | |
| SCHEMBL8931458 | 0.81 | MMP13 (0.59) | MMP13FDFT1MMP2MMP12 | |
| SCHEMBL8772636 | 0.79 | MMP13 (0.90) | MMP13FDFT1MMP2MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5654315-A | ENZYME INHIBITORS AS ANTICHOLESTEROL AGENTS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1997-08-05 | — | — | US | claimed |
| EP-0626960-A1 | QUINUCLIDINE DERIVATIVES AS SQUALENE SYNTHASE INHIBITORS | ZENECA LIMITED (GB) | 1994-12-07 | — | — | EP | claimed |
| US-5654315-A | ENZYME INHIBITORS AS ANTICHOLESTEROL AGENTS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1997-08-05 | — | — | US | disclosed |
| WO-1993013096-A1 | QUINUCLIDINE DERIVATIVES AS SQUALENE SYNTHASE INHIBITORS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-07-08 | — | — | WO | disclosed |