Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.38 |
| ▸ | CMKLR1 | Q99788 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8931843 | 0.92 | AGTR1 (0.40) | TAS2R14AGTR1AGTR2CMKLR1 | |
| SCHEMBL8931987 | 0.73 | LTB4R2 (0.41) | AGTR1AGTR2 | |
| SCHEMBL8931792 | 0.73 | AGTR1 (0.41) | AGTR1AGTR2 | |
| SCHEMBL8932041 | 0.69 | AGTR1 (0.41) | AGTR1AGTR2 | |
| SCHEMBL8931899 | 0.68 | CMKLR1 (0.42) | TAS2R14AGTR1AGTR2CMKLR1 | |
| SCHEMBL8911829 | 0.67 | CMKLR1 (0.44) | AGTR1AGTR2CMKLR1 | |
| SCHEMBL13113121 | 0.65 | MEN1 (0.66) | TAS2R14 | |
| SCHEMBL18427068 | 0.63 | ALDH1A1 (0.54) | AGTR1AGTR2 | |
| SCHEMBL8931838 | 0.63 | AGTR1 (0.44) | AGTR1AGTR2 | |
| SCHEMBL8931904 | 0.62 | AGTR1 (0.41) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5693633-A | Angiotensin II antagonists | ELI LILLY AND COMPANY (US) | 1997-12-02 | — | — | US | disclosed |