Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 5/20 | 0.44 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.44 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.44 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PTGIR | P43119 | 3/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8931994 | 0.71 | AGTR1 (0.49) | AGTR1AGTR2LTB4R2 | |
| SCHEMBL8931891 | 0.69 | AGTR1 (0.50) | AGTR1AGTR2ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL8931841 | 0.69 | AGTR1 (0.50) | AGTR1AGTR2ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL8931806 | 0.69 | AGTR1 (0.50) | AGTR1AGTR2ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL8931946 | 0.67 | AGTR1 (0.48) | AGTR1AGTR2 | |
| SCHEMBL8931835 | 0.66 | AGTR1 (0.44) | AGTR1AGTR2ALDH1A1MEN1KMT2A | |
| SCHEMBL19283593 | 0.65 | ALDH1A1 (0.53) | AGTR1AGTR2LTB4R2ALDH1A1MEN1 | |
| SCHEMBL8931824 | 0.65 | OPRK1 (0.51) | ALDH1A1MEN1KMT2AKDM4ETSHR | |
| SCHEMBL8931896 | 0.65 | AGTR1 (0.49) | AGTR1AGTR2ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL284853 | 0.64 | HDAC3 (0.56) | HTR1ADRD2MEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5693633-A | Angiotensin II antagonists | ELI LILLY AND COMPANY (US) | 1997-12-02 | — | — | US | disclosed |