Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK2 | O00142 | 7/20 | 0.32 |
| ▸ | NQO2 | P16083 | 3/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.31 |
| ▸ | TK1 | P04183 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8932014 | 0.91 | TK2 (0.30) | TK2 | |
| SCHEMBL8932073 | 0.89 | TK1 (0.34) | TK2TK1 | |
| SCHEMBL8932104 | 0.85 | MGAT2 (0.32) | TK1 | |
| SCHEMBL8932101 | 0.78 | HCRTR1 (0.32) | — | |
| SCHEMBL8932126 | 0.77 | NQO2 (0.31) | NQO2MTNR1AMTNR1B | |
| SCHEMBL6830773 | 0.75 | TK1 (0.35) | TK2TK1 | |
| SCHEMBL8932069 | 0.74 | TK1 (0.32) | TK2TK1 | |
| SCHEMBL8932076 | 0.74 | TYMP (0.39) | TK2TK1 | |
| SCHEMBL7603168 | 0.74 | TYMS (0.38) | TK2TK1 | |
| SCHEMBL7599693 | 0.74 | TYMS (0.38) | TK2TK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5681940-A | CONTAIN TETRAHYDROTHIOPHENE OR PYROLIDINE RINGS | ICN PHARMACEUTICALS (US) | 1997-10-28 | — | — | US | disclosed |