Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 2/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8932104 | 0.92 | MGAT2 (0.32) | HCRTR1HCRTR2 | |
| SCHEMBL8932014 | 0.85 | TK2 (0.30) | — | |
| SCHEMBL8932073 | 0.80 | TK1 (0.34) | — | |
| SCHEMBL8931993 | 0.80 | DTYMK (0.35) | — | |
| SCHEMBL8932016 | 0.78 | TK2 (0.32) | — | |
| SCHEMBL8517818 | 0.74 | DUT (0.31) | — | |
| SCHEMBL8931997 | 0.73 | TK1 (0.35) | — | |
| SCHEMBL9160674 | 0.71 | DTYMK (0.40) | — | |
| SCHEMBL9498388 | 0.71 | — | — | |
| SCHEMBL8932064 | 0.71 | FPR1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5681940-A | CONTAIN TETRAHYDROTHIOPHENE OR PYROLIDINE RINGS | ICN PHARMACEUTICALS (US) | 1997-10-28 | — | — | US | disclosed |