SCHEMBL8932150

SCHEMBL8932150

NC(=O)c1ccc(C(N)=O)c(-c2cccc(C(=O)Nc3ccccc3NC(=O)c3cccc(-c4cc(C(N)=O)ccc4C(N)=O)c3)c2)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDCD1 Q15116 1/20 0.53
CD274 Q9NZQ7 1/20 0.53
PLA2G2A P14555 1/20 0.49
SIRT2 Q8IXJ6 2/20 0.48
MEN1 O00255 4/20 0.48
KMT2A Q03164 4/20 0.48
SERPINE1 P05121 1/20 0.47
PKM P14618 1/20 0.47
RAB9A P51151 2/20 0.46
SUCNR1 Q9BXA5 1/20 0.46
NPC1 O15118 1/20 0.46
TERT O14746 1/20 0.46
TOP1 P11387 1/20 0.46
PLAU P00749 2/20 0.45
PLAT P00750 1/20 0.45
CDC7 O00311 1/20 0.44
PLK4 O00444 1/20 0.44
CHEK1 O14757 1/20 0.44
AURKA O14965 1/20 0.44
MAPK13 O15264 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3936438 0.87 PLAU (0.51) PLA2G2ASIRT2MEN1KMT2ATOP1
SCHEMBL8542133 0.86 PDCD1 (0.49) PDCD1CD274SIRT2MEN1KMT2A
SCHEMBL3265708 0.78 BCAT2 (0.63) PDCD1CD274PLA2G2ARAB9ANPC1
SCHEMBL28096188 0.77 BCAT2 (0.67) PLA2G2ARAB9ANPC1CHEK1FYN
SCHEMBL21295924 0.76 PLA2G2A (0.47) PLA2G2APLK4EGFRROS1PIM1
SCHEMBL6720875 0.75 MEN1 (0.73) PDCD1CD274SIRT2MEN1KMT2A
Dimethylamine SCHEMBL9236857 0.74 PARP1 (0.54) PLA2G2ACDC7CSF1RFLT1FLT3
SCHEMBL16438662 0.73 ALDH1A1 (0.49) MEN1KMT2ARAB9ANPC1CDC7
SCHEMBL29101462 0.73 MEN1 (0.57) SIRT2MEN1KMT2APKMRAB9A
SCHEMBL29400809 0.73 BCAT2 (0.47) PLA2G2AMEN1KMT2ARAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0792326-A2 ANTIFOULING PAINT COMPOSITION J.C. HEMPEL'S SKIBSFARVE-FABRIK A/S (DK) 1997-09-03 EP disclosed
WO-1996015198-A2 ANTIFOULING PAINT COMPOSITION J.C. HEMPEL'S SKIBSFARVE-FABRIK A/S (DK) 1996-05-23 WO disclosed