Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6647064 | 0.89 | — | — | |
| SCHEMBL8301431 | 0.84 | — | — | |
| SCHEMBL6208851 | 0.84 | GABRA1 (0.36) | — | |
| SCHEMBL3232243 | 0.81 | GABRA1 (0.45) | — | |
| SCHEMBL28438124 | 0.81 | — | — | |
| SCHEMBL9164495 | 0.80 | — | — | |
| SCHEMBL7857695 | 0.78 | — | — | |
| SCHEMBL28415052 | 0.77 | NR1I2 (0.33) | — | |
| SCHEMBL3059394 | 0.75 | GABRA1 (0.41) | — | |
| SCHEMBL15822716 | 0.75 | CTRC (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808313-A1 | ANTIPSYCHOTIC 4-(1H-INDOLYL-1-YL)-1-SUBSTITUTED PIPERIDINE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1997-11-26 | — | — | EP | disclosed |
| WO-1996023784-A1 | ANTIPSYCHOTIC 4-(1H-INDOLYL-1-YL)-1-SUBSTITUTED PIPERIDINE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1996-08-08 | — | — | WO | disclosed |