Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.31 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8932234 | 0.90 | KMT2A (0.49) | KMT2AADORA2AADORA1HDAC1HDAC8 | |
| SCHEMBL8932244 | 0.82 | KMT2A (0.48) | KMT2AADORA2AADORA1TGFBR1 | |
| SCHEMBL8932259 | 0.77 | PTGS1 (0.32) | — | |
| SCHEMBL8932311 | 0.77 | KMT2A (0.46) | KMT2AADORA2AADORA1TGFBR1 | |
| SCHEMBL8932302 | 0.77 | KMT2A (0.44) | KMT2AADORA2AADORA1TGFBR1 | |
| SCHEMBL8932343 | 0.75 | — | — | |
| SCHEMBL8932265 | 0.74 | ALDH1A1 (0.30) | — | |
| SCHEMBL8932284 | 0.74 | TGFBR1 (0.41) | KMT2AHDAC1HDAC8HDAC6HDAC5 | |
| SCHEMBL8932297 | 0.74 | KMT2A (0.48) | KMT2AADORA2AADORA1TGFBR1 | |
| SCHEMBL5547806 | 0.73 | KMT2A (0.50) | KMT2AADORA2AADORA1TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5536701-A | 3-pyrazolyloxypyridazines, herbicidal compositions and uses thereof | MONSANTO COMPANY (US) | 1996-07-16 | — | — | US | disclosed |