Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 2/20 | 0.32 |
| ▸ | NOS1 | P29475 | 2/20 | 0.32 |
| ▸ | NOS2 | P35228 | 2/20 | 0.32 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.31 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RBP4 | P02753 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8932246 | 0.80 | HTR2C (0.42) | HTR2CGAAHTR2BTDP1NOS3 | |
| SCHEMBL1068978 | 0.78 | NOS1 (0.41) | HTR2CGAANOS3NOS1NOS2 | |
| SCHEMBL7517456 | 0.78 | ADRA1A (0.40) | KDM4EMAPT | |
| SCHEMBL8932290 | 0.75 | GAA (0.39) | GAANOS3NOS1NOS2KDM4E | |
| SCHEMBL8786151 | 0.75 | GAA (0.39) | GAANOS3NOS1NOS2KDM4E | |
| SCHEMBL8932294 | 0.75 | GAA (0.39) | GAANOS3NOS1NOS2KDM4E | |
| SCHEMBL1067058 | 0.74 | KDM4E (0.44) | HTR2CGAANOS3NOS1NOS2 | |
| SCHEMBL8786474 | 0.73 | KDM4E (0.47) | HTR2CGAANOS3NOS1NOS2 | |
| SCHEMBL4849477 | 0.73 | KDM4E (0.47) | HTR2CGAANOS3NOS1NOS2 | |
| SCHEMBL570948 | 0.73 | KDM4E (0.47) | HTR2CGAANOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5498624-A | PLANT FUNGICIDES | MONSANTO COMPANY (US) | 1996-03-12 | — | — | US | disclosed |