Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.73 |
| ▸ | CTSS | P25774 | 2/20 | 0.73 |
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
| ▸ | MME | P08473 | 1/20 | 0.57 |
| ▸ | ECE1 | P42892 | 1/20 | 0.57 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | CTSB | P07858 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.49 |
| ▸ | BACE1 | P56817 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4804064 | 1.00 | CTSL (0.73) | CTSLCTSSATMMMEECE1 | |
| SCHEMBL8932375 | 0.86 | CTSS (0.69) | CTSLCTSSATMCTSKCYP1A2 | |
| SCHEMBL7886229 | 0.85 | CTSS (0.58) | CTSLCTSSATMMMEECE1 | |
| SCHEMBL2943917 | 0.85 | CTSS (0.67) | CTSLCTSSATMCTSBCTSK | |
| SCHEMBL2943915 | 0.85 | CTSS (0.67) | CTSLCTSSATMCTSBCTSK | |
| SCHEMBL11075199 | 0.83 | CTSL (0.67) | CTSLCTSSATMCASP1ALDH1A1 | |
| SCHEMBL3255533 | 0.83 | ATM (0.77) | CTSLCTSSATMCASP1ALDH1A1 | |
| SCHEMBL1362502 | 0.83 | ATM (0.77) | CTSLCTSSATMCASP1ALDH1A1 | |
| SCHEMBL7719287 | 0.83 | ATM (0.77) | CTSLCTSSATMCASP1ALDH1A1 | |
| SCHEMBL434233 | 0.83 | ATM (0.77) | CTSLCTSSATMCASP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996027370-A1 | FREE RADICAL SCAVENGER MOLECULES | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1996-09-12 | — | — | WO | disclosed |