Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 4/20 | 0.58 |
| ▸ | CTSL | P07711 | 3/20 | 0.58 |
| ▸ | CASP3 | P42574 | 4/20 | 0.51 |
| ▸ | CASP7 | P55210 | 4/20 | 0.51 |
| ▸ | CASP1 | P29466 | 4/20 | 0.51 |
| ▸ | CASP4 | P49662 | 2/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | CASP9 | P55211 | 2/20 | 0.51 |
| ▸ | CASP10 | Q92851 | 2/20 | 0.51 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.51 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 4/20 | 0.47 |
| ▸ | CTSB | P07858 | 2/20 | 0.47 |
| ▸ | MME | P08473 | 1/20 | 0.47 |
| ▸ | ECE1 | P42892 | 1/20 | 0.47 |
| ▸ | REN | P00797 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7878944 | 0.88 | CTSL (0.52) | CTSSCTSLCASP3CASP7CASP1 | |
| SCHEMBL8932368 | 0.85 | CTSL (0.73) | CTSSCTSLCASP1ATMCTSK | |
| SCHEMBL4804064 | 0.85 | CTSL (0.73) | CTSSCTSLCASP1ATMCTSK | |
| SCHEMBL7880623 | 0.84 | CASP3 (0.61) | CTSSCTSLCASP3CASP7CASP1 | |
| SCHEMBL28707519 | 0.81 | CASP1 (0.60) | CTSSCTSLCASP1CTSKCTSB | |
| SCHEMBL28707521 | 0.81 | CASP1 (0.60) | CTSSCTSLCASP1CTSKCTSB | |
| SCHEMBL7887042 | 0.81 | CASP3 (0.62) | CTSSCTSLCASP3CASP7CASP1 | |
| SCHEMBL16770335 | 0.80 | CASP3 (0.59) | CTSSCTSLCASP3CASP7CASP1 | |
| SCHEMBL11981402 | 0.80 | CTSS (0.58) | CTSSCTSLCASP1CTSKCTSB | |
| SCHEMBL9962106 | 0.78 | CASP3 (0.57) | CTSSCTSLCASP3CASP7CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010133000-A1 | SELECTIVE CASPASE INHIBITORS AND USES THEREOF | NEW WORLD LABORATORIES INC. (CA) | 2010-11-25 | — | — | WO | disclosed |