Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 6/20 | 0.58 |
| ▸ | MME | P08473 | 7/20 | 0.57 |
| ▸ | ACE2 | Q9BYF1 | 6/20 | 0.54 |
| ▸ | ACE | P12821 | 5/20 | 0.49 |
| ▸ | CPA1 | P15085 | 4/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7411242 | 0.88 | ACP3 (0.49) | ACP3MMEACE2ACECPA1 | |
| SCHEMBL7413350 | 0.87 | MME (0.50) | ACP3MMEACE2ACECPA1 | |
| SCHEMBL7410900 | 0.87 | MME (0.47) | ACP3MMEACE2ACECPA1 | |
| SCHEMBL7415759 | 0.87 | MME (0.49) | ACP3MMEACE2 | |
| SCHEMBL7414730 | 0.85 | ITGA4 (0.56) | — | |
| SCHEMBL7407922 | 0.85 | PTGDR (0.48) | ACP3MMEACE2 | |
| SCHEMBL7310433 | 0.83 | MMEL1 (0.60) | ACP3MMEACE | |
| SCHEMBL7322645 | 0.81 | MMEL1 (0.52) | ACP3 | |
| SCHEMBL7306720 | 0.81 | ACP3 (0.47) | ACP3MMEACE2 | |
| SCHEMBL7413501 | 0.80 | ECE1 (0.49) | ACP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996026729-A1 | PHOSPHONO SUBSTITUTED TETRAZOLE DERIVATIVES AS ECE INHIBITORS | CIBA-GEIGY AG (CH) | 1996-09-06 | — | — | WO | disclosed |