Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4711900 | 0.87 | KMT2A (0.48) | KMT2AMAPK1RAB9AALDH1A1MAPT | |
| SCHEMBL752241 | 0.85 | MMP2 (0.43) | KMT2ARAB9AALDH1A1MAPTMEN1 | |
| SCHEMBL4320013 | 0.82 | MAPK1 (0.40) | KMT2AMAPK1RAB9AALDH1A1MAPT | |
| SCHEMBL31605825 | 0.79 | KMT2A (0.40) | KMT2AMAPK1RAB9AALDH1A1MAPT | |
| SCHEMBL772374 | 0.78 | KMT2A (0.69) | KMT2AMAPK1RAB9AALDH1A1MAPT | |
| SCHEMBL17595505 | 0.76 | MAPK1 (0.59) | KMT2AMAPK1RAB9AALDH1A1MAPT | |
| SCHEMBL24325729 | 0.76 | ALDH1A1 (0.59) | KMT2AMAPK1RAB9AALDH1A1MAPT | |
| SCHEMBL12903756 | 0.76 | HPGD (0.51) | KMT2AMAPK1RAB9AALDH1A1MAPT | |
| SCHEMBL14948534 | 0.76 | MAPK1 (0.69) | KMT2AMAPK1RAB9AALDH1A1MAPT | |
| SCHEMBL27129497 | 0.76 | ALDH1A1 (0.59) | KMT2AMAPK1RAB9AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996026939-A1 | CARBAPENEM COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-09-06 | — | — | WO | disclosed |