Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 1/20 | 0.58 |
| ▸ | NOS1 | P29475 | 3/20 | 0.44 |
| ▸ | NOS3 | P29474 | 2/20 | 0.44 |
| ▸ | NOS2 | P35228 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1703486 | 0.80 | PLG (0.67) | PLGNOS1NOS3NOS2LMNA | |
| SCHEMBL164098 | 0.74 | PLG (1.00) | PLGNOS1NOS3NOS2CYP2D6 | |
| Hydrochloric Acid SCHEMBL11099753 | 0.72 | PLG (0.95) | PLGNOS1NOS3NOS2CYP2D6 | |
| SCHEMBL6947266 | 0.71 | PLG (0.44) | PLGNOS1NOS3NOS2LMNA | |
| SCHEMBL8932511 | 0.70 | PLG (0.54) | PLGNOS1NOS3NOS2LMNA | |
| SCHEMBL48868 | 0.69 | PLG (0.52) | PLGNOS1NOS3NOS2LMNA | |
| SCHEMBL17107788 | 0.69 | PLG (0.52) | PLGNOS1NOS3NOS2ALDH1A1 | |
| SCHEMBL17107786 | 0.69 | PLG (0.52) | PLGNOS1NOS3NOS2ALDH1A1 | |
| SCHEMBL9668481 | 0.69 | PLG (0.52) | PLGNOS1NOS3NOS2LMNA | |
| SCHEMBL8546705 | 0.68 | SLC22A2 (0.58) | NOS1NOS3NOS2MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996026939-A1 | CARBAPENEM COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-09-06 | — | — | WO | disclosed |