Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 1/20 | 0.52 |
| ▸ | NOS1 | P29475 | 4/20 | 0.44 |
| ▸ | NOS3 | P29474 | 3/20 | 0.44 |
| ▸ | NOS2 | P35228 | 3/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CHKA | P35790 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5935352 | 0.83 | ADRA2A (0.44) | NOS1NOS3NOS2MAPTADRA2A | |
| SCHEMBL664694 | 0.76 | NOS1 (0.52) | NOS1NOS3NOS2MAPTKMT2A | |
| SCHEMBL10533424 | 0.74 | HTR3E (0.54) | NOS1NOS3NOS2MAPTSMN1; SMN2 | |
| SCHEMBL27981470 | 0.73 | NOS1 (0.56) | NOS1NOS3NOS2ADRA2AADRA2B | |
| SCHEMBL27981468 | 0.73 | HTR3E (0.52) | NOS1NOS3NOS2ADRA2AADRA2B | |
| SCHEMBL19063477 | 0.73 | NOS1 (0.56) | NOS1NOS3NOS2MAPTSMN1; SMN2 | |
| SCHEMBL4008657 | 0.72 | CHRM5 (0.46) | PLGCHRM5CHKAMAPTSMN1; SMN2 | |
| SCHEMBL4008655 | 0.72 | CHRM5 (0.46) | PLGCHRM5CHKAMAPTSMN1; SMN2 | |
| SCHEMBL13967865 | 0.72 | NOS1 (0.33) | NOS1ADRA2AADRA2BADRA2C | |
| SCHEMBL5748747 | 0.71 | ADRA2A (0.54) | NOS1NOS3NOS2ADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129136-B2 | Kit for performing an assay | CYANAGEN SRL (IT) | 2012-03-06 | — | — | US | claimed |
| EP-1962095-B1 | Method for increasing light emission from a chemiluminescent reaction | CYANAGEN SRL (IT) | 2011-06-15 | — | — | EP | claimed |
| US-20110053200-A1 | Method for increasing light emission from a chemiluminescent reaction | CYANAGEN SRL (IT) | 2011-03-03 | — | — | US | claimed |
| US-7803573-B2 | Method for increasing light emission from a chemiluminescent reaction | CYANAGEN SRL (IT) | 2010-09-28 | — | — | US | claimed |
| US-20080241868-A1 | Method for increasing light emission from a chemiluminescent reaction | CYANAGEN SRL (IT) | 2008-10-02 | — | — | US | claimed |
| EP-1962095-A1 | Method for increasing light emission from a chemiluminescent reaction | Cyanagen Srl (IT) | 2008-08-27 | — | — | EP | claimed |
| EP-0287340-B1 | NOVEL ACYLATION PROCESS FOR THE SYNTHESIS OF HMG-COA REDUCTASE INHIBITORS | MERCK & CO. INC. (US) | 1993-09-29 | — | — | EP | claimed |
| US-4845237-A | ANTIHYPERCHOLESTEROLEMIC COMPOUNDS | MERCK & CO., INC. (US) | 1989-07-04 | — | — | US | claimed |
| EP-0287340-A2 | Novel acylation process for the synthesis of HMG-COA reductase inhibitors | MERCK & CO. INC. (US) | 1988-10-19 | — | — | EP | claimed |
| US-8129136-B2 | Kit for performing an assay | CYANAGEN SRL (IT) | 2012-03-06 | — | — | US | disclosed |
| US-8088923-B2 | Cyclic-fused beta-lactones and their synthesis | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2012-01-03 | — | — | US | disclosed |
| EP-1962095-B1 | Method for increasing light emission from a chemiluminescent reaction | CYANAGEN SRL (IT) | 2011-06-15 | — | — | EP | disclosed |
| US-20110053200-A1 | Method for increasing light emission from a chemiluminescent reaction | CYANAGEN SRL (IT) | 2011-03-03 | — | — | US | disclosed |
| US-7803573-B2 | Method for increasing light emission from a chemiluminescent reaction | CYANAGEN SRL (IT) | 2010-09-28 | — | — | US | disclosed |
| US-20080241868-A1 | Method for increasing light emission from a chemiluminescent reaction | CYANAGEN SRL (IT) | 2008-10-02 | — | — | US | disclosed |
| EP-1962095-A1 | Method for increasing light emission from a chemiluminescent reaction | Cyanagen Srl (IT) | 2008-08-27 | — | — | EP | disclosed |
| EP-0287340-B1 | NOVEL ACYLATION PROCESS FOR THE SYNTHESIS OF HMG-COA REDUCTASE INHIBITORS | MERCK & CO. INC. (US) | 1993-09-29 | — | — | EP | disclosed |
| US-4845237-A | ANTIHYPERCHOLESTEROLEMIC COMPOUNDS | MERCK & CO., INC. (US) | 1989-07-04 | — | — | US | disclosed |
| EP-0287340-A2 | Novel acylation process for the synthesis of HMG-COA reductase inhibitors | MERCK & CO. INC. (US) | 1988-10-19 | — | — | EP | disclosed |