Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 1/20 | 0.52 |
| ▸ | NOS3 | P29474 | 10/20 | 0.44 |
| ▸ | NOS1 | P29475 | 8/20 | 0.44 |
| ▸ | NOS2 | P35228 | 5/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.32 |
| ▸ | HTR3B | O95264 | 1/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.32 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.32 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.32 |
| ▸ | CLK2 | P49760 | 1/20 | 0.32 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17107786 | 0.73 | PLG (0.52) | PLGNOS3NOS1NOS2HTT | |
| SCHEMBL17107788 | 0.73 | PLG (0.52) | PLGNOS3NOS1NOS2HTT | |
| SCHEMBL8932511 | 0.70 | PLG (0.54) | PLGNOS3NOS1NOS2LMNA | |
| SCHEMBL8932568 | 0.69 | PLG (0.58) | PLGNOS3NOS1NOS2HTR3E | |
| SCHEMBL164098 | 0.69 | PLG (1.00) | PLGNOS3NOS1NOS2HTR3E | |
| SCHEMBL48868 | 0.68 | PLG (0.52) | PLGNOS3NOS1NOS2HTT | |
| Hydrochloric Acid SCHEMBL11099753 | 0.67 | PLG (0.95) | PLGNOS3NOS1NOS2HTR3E | |
| SCHEMBL10509447 | 0.65 | PLG (0.43) | PLGNOS3NOS1NOS2HTT | |
| SCHEMBL1703486 | 0.65 | PLG (0.67) | PLGNOS3NOS1NOS2L3MBTL1 | |
| SCHEMBL1746460 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0363061-B1 | IMIDAZOLINE DERIVATIVE AND PREPARATION THEREOF | TANABE SEIYAKU CO., LTD. (JP) | 1992-07-22 | — | — | EP | disclosed |
| US-5051441-A | Immunomodulators and cardiovascular disorders | TANABE SEIYAKU CO., LTD. (JP) | 1991-09-24 | — | — | US | disclosed |
| EP-0363061-A1 | Imidazoline derivative and preparation thereof | TANABE SEIYAKU CO., LTD. (JP) | 1990-04-11 | — | — | EP | disclosed |