Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 3/20 | 0.64 |
| ▸ | BCAT1 | P54687 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.47 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.47 |
| ▸ | FLT3 | P36888 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 2/20 | 0.47 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.47 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2576116 | 0.83 | XDH (0.56) | XDHBCAT1CYP2C9MMP2MMP13 | |
| SCHEMBL21770540 | 0.78 | KDM4E (0.67) | XDHPDGFRBPDGFRAFLT3KDM4E | |
| SCHEMBL29493369 | 0.77 | KDM4E (0.69) | XDHPDGFRBPDGFRAFLT3KDM4E | |
| SCHEMBL519591 | 0.77 | KDM4E (0.69) | XDHPDGFRBPDGFRAFLT3KDM4E | |
| SCHEMBL1104006 | 0.76 | PDGFRB (0.77) | XDHKMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL31361409 | 0.76 | PDGFRB (0.77) | XDHKMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL213638 | 0.75 | XDH (0.63) | XDHBCAT1KMT2AMEN1CYP1A2 | |
| Hydrochloric Acid SCHEMBL5159238 | 0.75 | KDM4E (0.67) | XDHPDGFRBPDGFRAFLT3KDM4E | |
| Hydrochloric Acid SCHEMBL4591208 | 0.75 | KDM4E (0.67) | XDHPDGFRBPDGFRAFLT3KDM4E | |
| SCHEMBL18814268 | 0.75 | HRH3 (0.72) | XDHKMT2AMEN1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996026207-A1 | THIAZOLIDINE AND OXAZOLIDINE INDOLES WITH HYPOCLYCEMIC ACTIVITY | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1996-08-29 | — | — | WO | disclosed |