Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3A | Q14432 | 3/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | MTOR | P42345 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.44 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.44 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.44 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.38 |
| ▸ | ALB | P02768 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.38 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | DNMT1 | P26358 | 2/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7794942 | 0.83 | PDE3A (0.46) | PDE3APDE4DSLC29A1LMNAMTOR | |
| SCHEMBL1939478 | 0.81 | PDE3A (0.47) | PDE3APDE4DSLC29A1LMNAMTOR | |
| SCHEMBL3424602 | 0.81 | PDE3A (0.47) | PDE3APDE4DSLC29A1LMNAMTOR | |
| SCHEMBL28379714 | 0.81 | PDE3A (0.47) | PDE3APDE4DSLC29A1LMNAMTOR | |
| SCHEMBL4971926 | 0.81 | PDE3A (0.46) | PDE3APDE4DSLC29A1LMNAMTOR | |
| SCHEMBL51650 | 0.81 | PDE3A (0.46) | PDE3APDE4DSLC29A1LMNAMTOR | |
| SCHEMBL3038818 | 0.81 | PDE3A (0.52) | PDE3APDE4DSLC29A1LMNAMTOR | |
| SCHEMBL3449198 | 0.81 | PDE3A (0.46) | PDE3APDE4DSLC29A1LMNAMTOR | |
| SCHEMBL992472 | 0.81 | PDE3A (0.46) | PDE3APDE4DSLC29A1LMNAMTOR | |
| SCHEMBL27544566 | 0.81 | PDE3A (0.46) | PDE3APDE4DSLC29A1LMNAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996023806-A1 | RAPID SYNTHESIS OF RADIOLABELED PYRIMIDINE NUCLEOSIDES OR NUCLEOTIDES | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1996-08-08 | — | — | WO | claimed |