SCHEMBL893277

SCHEMBL893277

O=C(Cl)c1cccc(C(=O)Cl)c1C(=O)Cl

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.56
ALOX15 P16050 2/20 0.52
TSHR P16473 2/20 0.39
CES2 O00748 4/20 0.39
CES1 P23141 4/20 0.39
BCHE P06276 1/20 0.36
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA7 P43166 1/20 0.35
CA9 Q16790 1/20 0.35
CA14 Q9ULX7 1/20 0.35
POLB P06746 1/20 0.34
NR4A1 P22736 1/20 0.34
NR4A2 P43354 1/20 0.34
NR4A3 Q92570 1/20 0.34
HSD17B10 Q99714 2/20 0.33
ALB P02768 1/20 0.33
G6PD P11413 1/20 0.33
CASP7 P55210 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10800604 0.93 ALDH1A1 (0.50) ALDH1A1ALOX15TSHRCES2CES1
SCHEMBL28269769 0.91 ALDH1A1 (0.50) ALDH1A1ALOX15TSHRCA12CA1
SCHEMBL1323054 0.85 CA12 (0.50) ALDH1A1ALOX15TSHRCA12CA1
SCHEMBL1846335 0.85 ALDH1A1 (0.74) ALDH1A1ALOX15TSHRCES2CES1
Hexane SCHEMBL27931599 0.85 TSHR (0.46) ALDH1A1ALOX15TSHRPOLBHSD17B10
SCHEMBL4921450 0.84 ALDH1A1 (0.46) ALDH1A1ALOX15TSHRHSD17B10HPGD
SCHEMBL301550 0.84 ALDH1A1 (0.46) ALDH1A1ALOX15POLBHSD17B10KDM4E
SCHEMBL31611275 0.84 ALDH1A1 (0.46) ALDH1A1ALOX15POLBHSD17B10KDM4E
SCHEMBL9836255 0.84 ALDH1A1 (0.65) ALDH1A1ALOX15CES2CES1BCHE
SCHEMBL4924666 0.84 ALDH1A1 (0.46) ALDH1A1ALOX15TSHRCES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 245 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12521683-B2 Reverse osmosis composite membrane with an ultrathin desalting layer and preparation method thereof VONTRON TECHNOLOGY CO., LTD. (CN) 2026-01-13 US claimed
CN-118594274-A Preparation method of reverse osmosis membrane and application of reverse osmosis membrane in sewage treatment 巴克夫化学有限公司 2024-09-06 CN claimed
US-20240091718-A1 REVERSE OSMOSIS COMPOSITE MEMBRANE WITH AN ULTRATHIN DESALTING LAYER AND PREPARATION METHOD THEREOF VONTRON TECHNOLOGY CO., LTD. (CN) 2024-03-21 US claimed
CN-115672033-A Anti-pollution and oxidation-resistant reverse osmosis membrane and preparation method thereof 万华化学集团股份有限公司 2023-02-03 CN claimed
US-10800883-B1 Optically transparent polyimide aerogels UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 2020-10-13 US claimed
US-10787569-B1 Process for preparing aerogels from polyamides UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 2020-09-29 US claimed
WO-2013005215-A2 PHMG MODIFIED ANTIMICROBIAL AGENTS STRAUSS WATER LTD. (IL) 2013-01-10 WO claimed
EP-0773481-B1 Photoconductive element containing polycarbonates crosslinked by aryltricarboxylic acids or their acid chlorides OCE TECH BV (NL) 2000-09-06 EP claimed
EP-0773481-A1 Photoconductive element containing polycarbonates crosslinked by aryltricarboxylic acids or their acid chlorides Océ-Nederland B.V. (NL) 1997-05-14 EP claimed
EP-0699702-A2 Reaction products of carbonyl compounds and dihydric phenols THE DOW CHEMICAL COMPANY (US) 1996-03-06 EP claimed
EP-0336999-A2 Reactive posttreatment for gas separation membranes L'AIR LIQUIDE, SOCIETE ANONYME POUR L'ETUDE ET L'EXPLOITATION DES PROCEDES GEORGES CLAUDE (FR) 1989-10-18 EP claimed
EP-0313354-A1 Reverse osmosis membranes and process for their production PCI MEMBRANE SYSTEMS LIMITED (GB) 1989-04-26 EP claimed
US-4704448-A MOLDING MATERIALS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1987-11-03 US claimed
EP-4724532-A1 REWORKABLE POLYSILOXANES FOR THERMAL INTERFACE MATERIALS International Business Machines Corporation (US) 2026-04-15 EP disclosed
US-12521683-B2 Reverse osmosis composite membrane with an ultrathin desalting layer and preparation method thereof VONTRON TECHNOLOGY CO., LTD. (CN) 2026-01-13 US disclosed
US-12257294-B2 Therapeutics for autoimmune disease: synthetic antigens DANMARKS TEKNISKE UNIVERSITET (DK) 2025-03-25 US disclosed
EP-0313354-A1 Reverse osmosis membranes and process for their production PCI MEMBRANE SYSTEMS LIMITED (GB) 1989-04-26 EP disclosed
US-4720537-A Branched copolyetherketones E. I. DU PONT DE NEMOURS AND COMPANY (US) 1988-01-19 US disclosed
EP-0229470-A1 Branched copolyetherketones E.I. DU PONT DE NEMOURS AND COMPANY (US) 1987-07-22 EP disclosed
US-4409201-A Pressure-resistant microcapsules with a polyamide shell and a polyurethane-polyurea inner mass and process for their manufacture HOECHST AKTIENGESELLSCHAFT (DE) 1983-10-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12257294-B2 Therapeutics for autoimmune disease: synthetic antigens SSB, HAVCR2, CD47 ALDH1A1 3003/4885ALOX15 3085/4885TSHR 365/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.