SCHEMBL301550

SCHEMBL301550

Cc1cccc(C(=O)Cl)c1C(=O)Cl

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.46
HPGD P15428 3/20 0.45
KDM4E B2RXH2 3/20 0.45
HSD17B10 Q99714 2/20 0.45
ALOX15 P16050 1/20 0.43
MYC P01106 1/20 0.41
L3MBTL1 Q9Y468 2/20 0.40
TDP1 Q9NUW8 2/20 0.39
CYP3A4 P08684 2/20 0.39
CYP2C9 P11712 2/20 0.39
KMT2A Q03164 2/20 0.39
POLB P06746 1/20 0.38
MEN1 O00255 1/20 0.37
AKR1B10 O60218 1/20 0.37
TRPA1 O75762 1/20 0.37
ABCB11 O95342 1/20 0.37
DHFR P00374 1/20 0.37
LMNA P02545 1/20 0.37
MPO P05164 1/20 0.37
CYP1A2 P05177 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31611275 1.00 ALDH1A1 (0.46) ALDH1A1HPGDKDM4EHSD17B10ALOX15
SCHEMBL5609242 0.88 ALDH1A1 (0.57) ALDH1A1HPGDKDM4EHSD17B10ALOX15
SCHEMBL247778 0.86 ALDH1A1 (0.54) ALDH1A1HPGDKDM4EHSD17B10MYC
Bromide SCHEMBL27753498 0.84 ALDH1A1 (0.52) ALDH1A1HPGDKDM4EHSD17B10MYC
SCHEMBL893277 0.84 ALDH1A1 (0.56) ALDH1A1HPGDKDM4EHSD17B10ALOX15
SCHEMBL27321464 0.83 AKR1C3 (0.46) ALDH1A1HPGDKDM4EHSD17B10ALOX15
SCHEMBL11101842 0.83 NR4A2 (0.47) ALDH1A1KDM4EHSD17B10ALOX15MYC
SCHEMBL93223 0.80 ESR1 (0.49) ALDH1A1HPGDKDM4EHSD17B10ALOX15
SCHEMBL29563004 0.80 MYC (0.52) ALDH1A1HPGDKDM4EHSD17B10ALOX15
SCHEMBL9712837 0.80 ALDH1A1 (0.39) ALDH1A1HPGDKDM4EHSD17B10L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115463551-B Aromatic polyamide water treatment separation membrane and preparation method thereof 盐城海普润科技股份有限公司 2023-06-06 CN claimed
CN-107983343-B Decarbonylation chlorination catalyst and preparation method and application thereof 上海化工研究院有限公司 2020-12-11 CN disclosed
CN-107000335-B Method and device for producing reinforced plastic parts 巴斯夫欧洲公司 2020-07-14 CN disclosed
EP-1758452-B1 METABOLICALLY STABLE ANALGESICS AND PAIN MEDICATIONS HUMAN BIOMOLECULAR RES INST (US) 2017-01-25 EP disclosed
US-20150011528-A1 PHENYLIMIDE-CONTAINING BENZOTHIAZOLE DERIVATIVE OF ITS SALT AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME YUHAN CORPORATION (KR) 2015-01-08 US disclosed
EP-2758384-A1 PHENYLIMIDE-CONTAINING BENZOTHIAZOLE DERIVATIVE OR ITS SALT AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME Yuhan Corporation (KR) 2014-07-30 EP disclosed
CN-103827099-A Phthalimide-containing benzothiazole derivative or salt thereof and pharmaceutical composition containing same YUHAN INC 2014-05-28 CN disclosed
US-8481501-B2 Synthesis of metabolically stable analgesics, pain medications and other agents HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) 2013-07-09 US disclosed
WO-2013043001-A1 PHENYLIMIDE-CONTAINING BENZOTHIAZOLE DERIVATIVE OR ITS SALT AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME YUHAN CORPORATION (KR) 2013-03-28 WO disclosed
US-20120255692-A1 Bleach compositions and related methods MARTIN ROY W (US) 2012-10-11 US disclosed
US-4404017-A APPLYING TO PLANTS, SEEDS, OR SOIL GULF OIL CORPORATION (US) 1983-09-13 US disclosed
US-4386201-A INCREASE OF FRUIT SET GULF OIL CORPORATION (US) 1983-05-31 US disclosed
EP-0009324-B1 SUBSTITUTED 1-BENZOYL-3-THIOSEMICARBAZIDES, THEIR MANUFACTURE AND USE AS PLANT GROWTH REGULANTS, AND AGRICULTURAL FORMULATIONS COMPRISING THEM Gulf Oil Corporation (US) 1982-07-21 EP disclosed
US-4339382-A Process for manufacturing N-arylthiocarbamoyl-2-amino-1H-isoindole-1,3-(2H)diones GULF OIL CORPORATION (US) 1982-07-13 US disclosed
EP-0043642-A1 Phthalimidoguanidines, a method of manufacturing same and the use thereof as plant growth regulators Gulf Oil Corporation (US) 1982-01-13 EP disclosed
US-4282031-A Substituted thiosemicarbazides, their manufacture and use as plant growth regulants GULF OIL CORPORATION (US) 1981-08-04 US disclosed
EP-0023766-A1 Phenyliminothiadiazolines, a method for manufacturing them and their application for regulating growth of plants Gulf Oil Corporation (US) 1981-02-11 EP disclosed
EP-0019369-A1 Isothioureido isoindolediones, process for their preparation and use as plant regulators Gulf Oil Corporation (US) 1980-11-26 EP disclosed
EP-0016571-A1 N-(Arylthiocarbamoyl)-2-amino-1H-isoindole-1,3-(2H)diones, processes for their preparation and their use as plant growth regulators Gulf Oil Corporation (US) 1980-10-01 EP disclosed
EP-0009324-A1 Substituted 1-benzoyl-3-thiosemicarbazides, their manufacture and use as plant growth regulants, and agricultural formulations comprising them Gulf Oil Corporation (US) 1980-04-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150011528-A1 PHENYLIMIDE-CONTAINING BENZOTHIAZOLE DERIVATIVE OF ITS SALT AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME ILK, PKMYT1, PLAUR ALDH1A1 3792/4885HPGD 3315/4885KDM4E 264/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.