Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 4/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.32 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.32 |
| ▸ | F2 | P00734 | 5/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | CPT2 | P23786 | 1/20 | 0.30 |
| ▸ | CPT1A | P50416 | 1/20 | 0.30 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.30 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.30 |
| ▸ | F10 | P00742 | 1/20 | 0.30 |
| ▸ | PLG | P00747 | 1/20 | 0.30 |
| ▸ | PLAT | P00750 | 1/20 | 0.30 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.30 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.30 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8933164 | 0.95 | ITGB3 (0.33) | ITGB3ITGA2BOPRK1KCNH2PARP15 | |
| SCHEMBL6487237 | 0.84 | ITGB3 (0.37) | ITGB3ITGA2BOPRK1KCNH2PARP15 | |
| SCHEMBL6476401 | 0.81 | ITGB3 (0.36) | ITGB3ITGA2BOPRK1KCNH2OPRM1 | |
| SCHEMBL6476618 | 0.80 | ITGB3 (0.36) | ITGB3ITGA2BOPRK1KCNH2PARP15 | |
| SCHEMBL6484205 | 0.74 | ITGB3 (0.35) | ITGB3ITGA2BOPRK1KCNH2OPRM1 | |
| SCHEMBL6477218 | 0.73 | OPRK1 (0.33) | ITGB3ITGA2BOPRK1KCNH2OPRM1 | |
| SCHEMBL6487745 | 0.72 | ITGB3 (0.36) | ITGB3ITGA2BOPRK1KCNH2OPRM1 | |
| SCHEMBL6477039 | 0.72 | ITGB3 (0.34) | ITGB3ITGA2BOPRK1KCNH2OPRM1 | |
| SCHEMBL6484317 | 0.72 | ITGB3 (0.37) | ITGB3ITGA2BOPRK1KCNH2PARP15 | |
| SCHEMBL6475867 | 0.71 | ITGB3 (0.34) | ITGB3ITGA2BOPRK1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996025426-A1 | NOVEL DIPEPTIDE AMIDINES AS THROMBIN INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 1996-08-22 | — | — | WO | disclosed |