SCHEMBL8933164

SCHEMBL8933164

N=C(N)c1ccc(C(N)=O)cn1.NCC(=O)N1CCCCC1(OC(=O)O)C1CCCCC1

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ITGB3 P05106 1/20 0.33
ITGA2B P08514 1/20 0.33
OPRK1 P41145 3/20 0.32
KCNH2 Q12809 1/20 0.32
CPT2 P23786 1/20 0.31
CPT1A P50416 1/20 0.31
CPT1B Q92523 1/20 0.31
OPRM1 P35372 2/20 0.31
HRH3 Q9Y5N1 2/20 0.31
PARP15 Q460N3 1/20 0.31
PARP10 Q53GL7 1/20 0.31
L3MBTL3 Q96JM7 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
F2 P00734 1/20 0.30
OPRD1 P41143 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8933045 0.95 ITGB3 (0.34) ITGB3ITGA2BOPRK1KCNH2CPT2
SCHEMBL6476401 0.85 ITGB3 (0.36) ITGB3ITGA2BOPRK1KCNH2CPT2
SCHEMBL6487237 0.81 ITGB3 (0.37) ITGB3ITGA2BOPRK1KCNH2CPT2
SCHEMBL6476618 0.79 ITGB3 (0.36) ITGB3ITGA2BOPRK1KCNH2OPRM1
SCHEMBL6484205 0.75 ITGB3 (0.35) ITGB3ITGA2BOPRK1KCNH2OPRM1
SCHEMBL6477218 0.73 OPRK1 (0.33) ITGB3ITGA2BOPRK1KCNH2OPRM1
SCHEMBL6487745 0.72 ITGB3 (0.36) ITGB3ITGA2BOPRK1KCNH2OPRM1
SCHEMBL6477039 0.72 ITGB3 (0.34) ITGB3ITGA2BOPRK1KCNH2OPRM1
SCHEMBL6475867 0.72 ITGB3 (0.34) ITGB3ITGA2BOPRK1KCNH2
SCHEMBL6485408 0.72 ITGB3 (0.34) ITGB3ITGA2BOPRK1KCNH2OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1996025426-A1 NOVEL DIPEPTIDE AMIDINES AS THROMBIN INHIBITORS BASF AKTIENGESELLSCHAFT (DE) 1996-08-22 WO disclosed