Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 1/20 | 0.57 |
| ▸ | LTA4H | P09960 | 3/20 | 0.48 |
| ▸ | PLG | P00747 | 1/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.48 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | BCL2 | P10415 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.46 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.46 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.46 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8933139 | 0.92 | REN (0.55) | RENLTA4HPLGPRSS1PRSS2 | |
| SCHEMBL7315183 | 0.83 | CA12 (0.62) | PTPN1ITGB3ITGA2BCA12CA1 | |
| SCHEMBL28577195 | 0.82 | CA12 (0.60) | PTPN1L3MBTL1ITGB3ITGA2BCA12 | |
| SCHEMBL2025554 | 0.82 | CA12 (0.60) | PTPN1L3MBTL1ITGB3ITGA2BCA12 | |
| Dl-Phenylalanine SCHEMBL28707890 | 0.81 | SLC7A5 (0.51) | TDP1CA1CA2 | |
| SCHEMBL3499282 | 0.80 | LTA4H (0.54) | LTA4HPTPN1BCL2LNPEPPPARG | |
| SCHEMBL7275476 | 0.80 | BCHE (0.56) | LTA4HHDAC1CA12CA1CA2 | |
| SCHEMBL30440340 | 0.80 | CA12 (0.63) | L3MBTL1HTTHDAC1NPC1LMNA | |
| SCHEMBL7806363 | 0.79 | LTA4H (0.56) | LTA4HPTPN1BCL2HDAC1LNPEP | |
| SCHEMBL515522 | 0.79 | SLC7A5 (0.69) | LTA4HITGB3ITGA2BPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996022962-A9 | BUTYRYL-TYROSINYL SPERMINE, ANALOGS THEREOF AND METHODS OF PREPARING AND USING SAME | — | 1996-10-03 | — | — | WO | disclosed |
| WO-1996022962-A1 | BUTYRYL-TYROSINYL SPERMINE, ANALOGS THEREOF AND METHODS OF PREPARING AND USING SAME | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 1996-08-01 | — | — | WO | disclosed |