Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | CPT2 | P23786 | 1/20 | 0.31 |
| ▸ | CPT1A | P50416 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.31 |
| ▸ | TACR3 | P29371 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8725915 | 0.88 | OPRM1 (0.30) | OPRM1OPRK1 | |
| SCHEMBL8933077 | 0.85 | — | — | |
| SCHEMBL6477215 | 0.85 | JAK2 (0.37) | GPR119JAK2JAK1CTSSCTSK | |
| SCHEMBL6476534 | 0.85 | JAK2 (0.36) | GPR119JAK2JAK1CTSSCTSK | |
| SCHEMBL6477307 | 0.82 | CTSS (0.34) | JAK2JAK1CTSSCTSKCPT2 | |
| SCHEMBL8933278 | 0.79 | OPRK1 (0.32) | OPRK1 | |
| SCHEMBL8722615 | 0.77 | HRH3 (0.34) | OPRK1 | |
| SCHEMBL8725919 | 0.77 | — | — | |
| SCHEMBL6489531 | 0.74 | NPFFR1 (0.35) | OPRM1OPRK1OPRD1 | |
| SCHEMBL8722553 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996025426-A1 | NOVEL DIPEPTIDE AMIDINES AS THROMBIN INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 1996-08-22 | — | — | WO | disclosed |