Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.40 |
| ▸ | MGAM | O43451 | 4/20 | 0.40 |
| ▸ | AMY1A | P0DUB6 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | SI | P14410 | 4/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3853512 | 0.87 | SLC9A1 (0.55) | SLC9A1POLBMAPK1ATMKEAP1 | |
| SCHEMBL19617512 | 0.83 | SLC9A1 (0.48) | SLC9A1POLBMAPK1ATMKEAP1 | |
| SCHEMBL628179 | 0.83 | SLC9A1 (0.48) | SLC9A1POLBMAPK1ATMKEAP1 | |
| SCHEMBL19515117 | 0.77 | POLB (0.75) | SLC9A1POLBMAPK1ATMKEAP1 | |
| SCHEMBL380082 | 0.70 | TSHR (0.44) | SLC9A1POLBMAPK1ATMKEAP1 | |
| SCHEMBL9618513 | 0.69 | POLB (0.52) | SLC9A1POLBMAPK1ATMKEAP1 | |
| SCHEMBL30363379 | 0.69 | POLB (0.52) | SLC9A1POLBMAPK1ATMKEAP1 | |
| Phosphoric Acid SCHEMBL3485078 | 0.69 | POLB (0.81) | SLC9A1POLBMAPK1ATMKEAP1 | |
| SCHEMBL448453 | 0.69 | HDAC3 (0.41) | SLC9A1POLBMAPK1ATMKEAP1 | |
| SCHEMBL15878936 | 0.67 | ALDH1A1 (0.56) | MAPK1GAAKMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996023813-A1 | PEPTIDES AND COMPOUNDS THAT BIND TO SH2 DOMAINS | AFFYMAX TECHNOLOGIES N.V. (AN) | 1996-08-08 | — | — | WO | disclosed |