Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 11/20 | 0.55 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CYP4Z1 | Q86W10 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | THPO | P40225 | 1/20 | 0.50 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.46 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19617512 | 0.93 | SLC9A1 (0.48) | SLC9A1KEAP1ALDH1A1CYP4Z1POLB | |
| SCHEMBL628179 | 0.93 | SLC9A1 (0.48) | SLC9A1KEAP1ALDH1A1CYP4Z1POLB | |
| SCHEMBL8933157 | 0.87 | SLC9A1 (0.43) | SLC9A1KEAP1ALDH1A1CYP4Z1POLB | |
| SCHEMBL15878936 | 0.73 | ALDH1A1 (0.56) | ALDH1A1MAPK1CYP1A2CYP3A4MAPT | |
| SCHEMBL170155 | 0.71 | SLC9A1 (1.00) | SLC9A1KEAP1ALDH1A1CYP4Z1POLB | |
| SCHEMBL29720118 | 0.71 | SLC9A1 (1.00) | SLC9A1KEAP1ALDH1A1CYP4Z1POLB | |
| SCHEMBL326359 | 0.71 | TUBB4A (0.39) | SLC9A1KEAP1ALDH1A1POLBRAB9A | |
| SCHEMBL3072391 | 0.70 | SLC9A1 (0.60) | SLC9A1KEAP1ALDH1A1CYP4Z1POLB | |
| Ammonia Solution, Strong SCHEMBL4635177 | 0.70 | SLC9A1 (0.95) | SLC9A1KEAP1ALDH1A1CYP4Z1POLB | |
| SCHEMBL2925766 | 0.70 | SLC9A1 (0.95) | SLC9A1KEAP1ALDH1A1CYP4Z1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3160985-B1 | PROCESS FOR THE PRODUCTION OF D-ARGINYL-2,6-DIMETHYL-L-TYROSYL-L-LYSYL-L-PHENYLALANINAMIDE | FLAMMA SPA (IT) | 2021-07-28 | — | — | EP | claimed |
| EP-3177635-B1 | PROCESSES FOR THE PREPARATION OF OXYTOCIN ANALOGUES | HOFFMANN LA ROCHE (CH) | 2018-10-03 | — | — | EP | claimed |
| CN-113518784-A | Therapeutic peptides | 科巴公司 | 2021-10-19 | — | — | CN | disclosed |
| CN-110997693-A | Tau aggregation inhibitors | 阿德克斯公司 | 2020-04-10 | — | — | CN | disclosed |
| US-10471020-B2 | Nanoparticles with protected interiors, and methods of use thereof | UNIVERSIDADE DE SANTIAGO DE COMPOSTELA (ES) | 2019-11-12 | — | — | US | disclosed |
| US-20180078510-A1 | NANOPARTICLES WITH PROTECTED INTERIORS, AND METHODS OF USE THEREOF | UNIVERSIDADE DE SANTIAGO DE COMPOSTELA (ES) | 2018-03-22 | — | — | US | disclosed |
| EP-2108012-A2 | SUBSTITUTED N-(4-CYANO-1H-PYRAZOL-3-YL)METHYLAMINE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | Sanofi-Aventis (FR) | 2009-10-14 | — | — | EP | disclosed |
| EP-1979350-A1 | ARYL-ISOXAZOL-4-YL-IMIDAZO[1,2-A]PYRIDINE USEFUL FOR THE TREATMENT OF ALZHEIMER'S DISEASE VIA GABA RECEPTORS | F.HOFFMANN-LA ROCHE AG (CH) | 2008-10-15 | — | — | EP | disclosed |
| WO-2008099076-A2 | SUBSTITUTED N-(4-CYANO-1H-PYRAZOL-3-YL)METHYLAMINE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2008-08-21 | — | — | WO | disclosed |
| US-7411065-B2 | Peptide nucleic acid monomers: diphenylmethyl, benzyl, alkylthioalkyl, or phenylthioalkyl esters of N-(1-[4-(2-benzothiazolyl-, 2-benzoxazolyl-, 2-benzofuranyl- or 2-benzothiophenyl-sulfonyl)-3-piperazinon-1-ylcarbonylmethyl]pyrimidon-4-yl)carbamic acids | PANAGENE, INC. (KR) | 2008-08-12 | — | — | US | disclosed |
| WO-2007082806-A1 | ARYL-ISOXAZOL-4-YL-IMIDAZO[1,2-A]PYRIDINE USEFUL FOR THE TREATMENT OF ALZHEIMER’S DISEASE VIA GABA RECEPTORS | F. HOFFMANN-LA ROCHE AG (CH) | 2007-07-26 | — | — | WO | disclosed |