SCHEMBL8933239

SCHEMBL8933239

C[C@H](Cl)Nn1ccc(=O)[nH]c1=O

nearest known ligand 0.47

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 3/20 0.47
PKM P14618 1/20 0.39
DDB1 Q16531 1/20 0.39
DUT P33316 5/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
HTT P42858 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11389897 0.84 CRBN (0.46) CRBNPKMDDB1DUTALDH1A1
SCHEMBL12099167 0.80 CRBN (0.42) CRBNPKMDDB1DUTALDH1A1
SCHEMBL3541014 0.76 CRBN (0.54) CRBNPKMDDB1DUTALDH1A1
SCHEMBL7030201 0.74 CRBN (0.43) CRBNPKMDDB1DUTL3MBTL1
SCHEMBL7926412 0.74 PKM (0.40) CRBNPKMDDB1DUTALDH1A1
Water SCHEMBL7316631 0.73 CRBN (0.42) CRBNPKMDDB1DUTL3MBTL1
SCHEMBL2181554 0.72 CRBN (0.54) CRBNPKMDDB1DUTL3MBTL1
SCHEMBL28414334 0.70 CRBN (0.47) CRBNDDB1DUTALDH1A1LMNA
SCHEMBL30479438 0.70 CRBN (0.47) CRBNPKMDDB1DUTL3MBTL1
SCHEMBL8933242 0.69 CRBN (0.41) CRBNPKMDDB1DUTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1996024558-A1 METHOD AND APPARATUS FOR THERMAL DECOMPOSITION AND SEPARATION OF COMPONENTS WITHIN AN AQUEOUS STREAM HPR CORPORATION (US) 1996-08-15 WO disclosed