SCHEMBL7926412

SCHEMBL7926412

CCCC(O)Nn1ccc(=O)[nH]c1=O

nearest known ligand 0.43

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.40
CRBN Q96SW2 4/20 0.40
DUT P33316 7/20 0.37
ALDH1A1 P00352 1/20 0.35
LMNA P02545 1/20 0.35
DDB1 Q16531 1/20 0.33
GAA P10253 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11389897 0.79 CRBN (0.46) PKMCRBNDUTALDH1A1LMNA
SCHEMBL8933239 0.74 CRBN (0.47) PKMCRBNDUTALDH1A1LMNA
SCHEMBL7632468 0.74 CRBN (0.47) PKMCRBNDUTALDH1A1LMNA
SCHEMBL21602127 0.68 CRBN (0.44) PKMCRBNDUTALDH1A1DDB1
SCHEMBL19187082 0.68 CRBN (0.44) PKMCRBNDUTDDB1
SCHEMBL25430771 0.68 GPR84 (0.44) CRBN
SCHEMBL7030201 0.67 CRBN (0.43) PKMCRBNDUTALDH1A1LMNA
SCHEMBL24023212 0.66 PKM (0.42) PKMCRBNDUTALDH1A1DDB1
SCHEMBL2181554 0.65 CRBN (0.54) PKMCRBNDUTALDH1A1LMNA
SCHEMBL19137754 0.65 DUT (0.36) PKMCRBNDUTALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6232375-B1 POLYVINYL CHLORIDE WITCO VINYL ADDITIVES GMBH (DE) 2001-05-15 US disclosed