Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8933373 | 1.00 | RAB9A (0.49) | RAB9AKMT2ANPC1TDP1L3MBTL1 | |
| SCHEMBL8933333 | 0.83 | MAPT (0.49) | RAB9AKMT2ANPC1TDP1L3MBTL1 | |
| SCHEMBL7159701 | 0.83 | MAPT (0.49) | RAB9AKMT2ANPC1TDP1L3MBTL1 | |
| SCHEMBL11461100 | 0.81 | NPSR1 (0.44) | RAB9ANPC1TDP1CYP1A2CYP2C19 | |
| SCHEMBL8933378 | 0.80 | RAB9A (0.43) | RAB9AKMT2ATDP1L3MBTL1CYP1A2 | |
| SCHEMBL8933376 | 0.80 | RAB9A (0.43) | RAB9AKMT2ATDP1L3MBTL1CYP1A2 | |
| SCHEMBL30770163 | 0.79 | RAB9A (0.48) | RAB9AKMT2ANPC1TDP1L3MBTL1 | |
| SCHEMBL5619493 | 0.79 | RAB9A (0.48) | RAB9AKMT2ANPC1TDP1L3MBTL1 | |
| SCHEMBL11614572 | 0.77 | KMT2A (0.49) | RAB9AKMT2ANPC1TDP1L3MBTL1 | |
| SCHEMBL9756557 | 0.75 | ALDH1A1 (0.46) | TDP1CYP1A2CYP2C19POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996024601-A1 | COMPLEXES, PROCESSES FOR THEIR PREPARATION AND THEIR USE | UNIVERSITY COLLEGE DUBLIN (IE) | 1996-08-15 | — | — | WO | claimed |
| WO-1996024601-A1 | COMPLEXES, PROCESSES FOR THEIR PREPARATION AND THEIR USE | UNIVERSITY COLLEGE DUBLIN (IE) | 1996-08-15 | — | — | WO | disclosed |