Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | ACP3 | P15309 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7159701 | 1.00 | MAPT (0.49) | MAPTRAB9AKMT2ANPC1TDP1 | |
| SCHEMBL5619493 | 0.97 | RAB9A (0.48) | MAPTRAB9AKMT2ANPC1TDP1 | |
| SCHEMBL30770163 | 0.94 | RAB9A (0.48) | MAPTRAB9AKMT2ANPC1TDP1 | |
| SCHEMBL14339295 | 0.87 | LMNA (0.46) | RAB9AKMT2ANPC1TDP1L3MBTL1 | |
| SCHEMBL12918603 | 0.86 | MAPT (0.48) | MAPTRAB9AKMT2ANPC1TDP1 | |
| SCHEMBL14339278 | 0.85 | LMNA (0.45) | RAB9AKMT2ANPC1TDP1L3MBTL1 | |
| SCHEMBL14339284 | 0.85 | LMNA (0.45) | RAB9AKMT2ANPC1TDP1L3MBTL1 | |
| SCHEMBL14339276 | 0.85 | LMNA (0.45) | RAB9AKMT2ANPC1TDP1L3MBTL1 | |
| SCHEMBL29644308 | 0.85 | POLB (0.47) | RAB9AKMT2ANPC1TDP1L3MBTL1 | |
| SCHEMBL9422307 | 0.85 | POLB (0.47) | RAB9AKMT2ANPC1TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996024601-A1 | COMPLEXES, PROCESSES FOR THEIR PREPARATION AND THEIR USE | UNIVERSITY COLLEGE DUBLIN (IE) | 1996-08-15 | — | — | WO | claimed |
| WO-1996024601-A1 | COMPLEXES, PROCESSES FOR THEIR PREPARATION AND THEIR USE | UNIVERSITY COLLEGE DUBLIN (IE) | 1996-08-15 | — | — | WO | disclosed |