Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 10/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 12/20 | 0.43 |
| ▸ | MEN1 | O00255 | 11/20 | 0.43 |
| ▸ | POLB | P06746 | 6/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | RECQL | P46063 | 4/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.41 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8310606 | 0.88 | MAPT (0.56) | FABP4MAPTKMT2AMEN1POLB | |
| SCHEMBL8537294 | 0.81 | IGF1R (0.38) | FABP4MAPTKMT2AMEN1POLB | |
| SCHEMBL8307820 | 0.80 | DYRK1A (0.61) | MAPTKMT2AMEN1POLBGAA | |
| SCHEMBL8933459 | 0.80 | KMT2A (0.46) | FABP4MAPTKMT2AMEN1POLB | |
| SCHEMBL8991958 | 0.80 | KMT2A (0.46) | FABP4MAPTKMT2AMEN1POLB | |
| SCHEMBL8986231 | 0.80 | KMT2A (0.46) | FABP4MAPTKMT2AMEN1POLB | |
| SCHEMBL8933494 | 0.78 | IGF1R (0.40) | FABP4MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL8532185 | 0.78 | MEN1 (0.66) | FABP4MAPTKMT2AMEN1POLB | |
| SCHEMBL8532182 | 0.78 | MEN1 (0.66) | FABP4MAPTKMT2AMEN1POLB | |
| SCHEMBL8933559 | 0.75 | IGF1R (0.45) | MAPTKMT2AMEN1POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996022772-A1 | METHOD FOR TREATING MULTIPLE SCLEROSIS | ELI LILLY AND COMPANY (US) | 1996-08-01 | — | — | WO | disclosed |
| EP-0722729-A2 | Aryl-substituted rhodanines for treating multiple sclerosis | ELI LILLY AND COMPANY (US) | 1996-07-24 | — | — | EP | disclosed |
| US-5523314-A | RHODANINE DERIVATIVES | ELI LILLY AND COMPANY (US) | 1996-06-04 | — | — | US | disclosed |