Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 11/20 | 0.69 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.56 |
| ▸ | EGFR | P00533 | 1/20 | 0.56 |
| ▸ | CDK1 | P06493 | 1/20 | 0.56 |
| ▸ | CDK4 | P11802 | 1/20 | 0.56 |
| ▸ | SRC | P12931 | 1/20 | 0.56 |
| ▸ | CCND1 | P24385 | 1/20 | 0.56 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.56 |
| ▸ | CDK2 | P24941 | 1/20 | 0.56 |
| ▸ | KDR | P35968 | 1/20 | 0.56 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.56 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.50 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.50 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.50 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10404819 | 0.86 | ALOX12 (0.72) | CHRM1CCNE2EGFRCDK1CDK4 | |
| SCHEMBL7320239 | 0.86 | GABRA1 (0.69) | CHRM1CCNE2EGFRCDK1CDK4 | |
| SCHEMBL7321076 | 0.84 | CHRM1 (0.67) | CHRM1CCNE2EGFRCDK1CDK4 | |
| SCHEMBL7324382 | 0.84 | CHRM1 (0.77) | CHRM1CCNE2CCNE1CDK2ALOX12 | |
| SCHEMBL11733109 | 0.82 | CHRM1 (0.73) | CHRM1CCNE2CCNE1CDK2ALOX12 | |
| SCHEMBL30320323 | 0.81 | CHRM1 (1.00) | CHRM1CCNE2CCNE1CDK2ALOX12 | |
| SCHEMBL7324283 | 0.81 | CHRM1 (0.73) | CHRM1ALOX12SMN1; SMN2GABRA1GABRA5 | |
| SCHEMBL7950385 | 0.81 | CHRM1 (1.00) | CHRM1ALOX12SMN1; SMN2GABRA1GABRA5 | |
| SCHEMBL7328311 | 0.81 | CHRM1 (1.00) | CHRM1CCNE2CCNE1CDK2ALOX12 | |
| SCHEMBL11825759 | 0.80 | CHRM1 (0.74) | CHRM1ALOX12SMN1; SMN2GABRA1GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996023790-A1 | ACETYLIMIDAZOBENZODIAZEPINES | F. HOFFMANN-LA ROCHE AG (CH) | 1996-08-08 | — | — | WO | disclosed |
| US-3933794-A | CENTRAL NERVOUS SYSTEM DEPRESSANTS | THE UPJOHN COMPANY (US) | 1976-01-20 | — | — | US | disclosed |